{"id":19002,"date":"2022-01-17T09:59:51","date_gmt":"2022-01-17T08:59:51","guid":{"rendered":"https:\/\/www.idisantiago.es\/grupo-de-investigacion\/c042-ictus-traslacional\/"},"modified":"2026-04-10T10:07:43","modified_gmt":"2026-04-10T08:07:43","slug":"c042-ictus-traslacional","status":"publish","type":"project","link":"https:\/\/www.idisantiago.es\/en\/grupo-de-investigacion\/c042-ictus-traslacional\/","title":{"rendered":"C042 &#8211; Translational Stroke"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||||false|false&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; custom_padding=&#8221;0px||||false|false&#8221; locked=&#8221;on&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>\u00c1REA: <a href=\"https:\/\/www.idisantiago.es\/en\/research-areas-2\/a004-neurociencias\/\">NEUROCIENCIAS<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;2_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.idisantiago.es\/wp-content\/uploads\/2022\/02\/C042_B.jpg&#8221; title_text=&#8221;C042_B&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_toggle title=&#8221;Objectives and lines of research&#8221; admin_label=&#8221;Objetivos y l\u00edneas de investigaci\u00f3n&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Objectives<\/h3>\n<p>Study and development of new therapeutic strategies in neuronal pathologies, mainly related to cerebral ischemia. Our perspective is to try that all the knowledge developed in the field of research has a translational application and that it has an impact on the benefit of the patient.<\/p>\n<h3>Lines of research<\/h3>\n<p>1. Neuroprotection against excitotoxic damage in cerebral ischemia and ALS.<br \/>2. Study of molecular mechanisms related to hypothermia in cerebral ischemia.<br \/>3. Development of nanostructures for the encapsulation and controlled release of drugs in ischemic brain pathology.<br \/>4. Use of cell technology based on the generation of induced pluripotent stem cells (iPSCs) in monogenic diseases that cause stroke.<br \/>5. Analysis of biomarkers associated with diagnosis in cerebral stroke.<\/p>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Research team&#8221; admin_label=&#8221;Equipo investigador&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<table style=\"width: 100%; border-collapse: collapse; border-style: hidden;\" border=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\"><strong>Leader<\/strong><br \/>Campos P\u00e9rez, Francisco<strong>Members<\/strong><br \/>Arias Rivas, Susana<br \/>Bugallo Casal, Ana Isabel<br \/>Candamo Lourido, Mar\u00eda<br \/>Ca\u00f1izo Outeiri\u00f1o, Antonio<br \/>Del Pozo Fil\u00edu, Luc\u00eda<br \/>Dopico L\u00f3pez, Antonio<br \/>Garc\u00eda Sobrino, Tania<br \/>Laso Garc\u00eda, Fernando<br \/>L\u00f3pez Arias, Esteban<br \/>Otero Rial, Noelia<br \/>Palomar Alonso, Nuria<br \/>Pardo Fern\u00e1ndez, Julio<br \/>P\u00e9rez Gayol, Lara<br \/>P\u00e9rez L\u00e1zaro, Sonia<br \/>P\u00e9rez Mato, Mar\u00eda<br \/>Prego Dom\u00ednguez, Jes\u00fas<br \/>Rodr\u00edguez Y\u00e1\u00f1ez, Manuel<br \/>Santamar\u00eda Cadavid, Mar\u00eda<\/td>\n<td style=\"width: 50%;\">\u00a0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Projects&#8221; admin_label=&#8221;Proyectos (cambiar s\u00f3 codigo IDIS)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; locked=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Publications&#8221; admin_label=&#8221;Publicaciones&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li>Migliavacca M, Correa Paz C, P\u00e9rez-Mato M, Bielawski PB, Zhang I, Marie P, Hervella P, Rubio M, Maysinger D, Vivien D, Del Pino P, Pelaz B, Polo E, Campos F. <strong>Thrombolytic therapy based on lyophilized platelet-derived nanocarriers for ischemic stroke.<\/strong> <em>J Nanobiotechnology<\/em> 2024 <a href=\"https:\/\/doi.org\/10.1186\/s12951-023-02206-5\"><span style=\"color: #808000;\"><strong>DOI: 10.1186\/s12951-023-02206-5<\/strong><\/span><\/a><\/li>\n<li>Surpi A, Murgia M, L\u00f3pez-Amoedo S, Gonz\u00e1lez-G\u00f3mez MA, Pi\u00f1eiro Y, Rivas J, Perugini V, Santin M, Sobrino T, Greco P, Campos F and Dediu VA. <strong>Magnetic separation and concentration of A\u03b2 1-42 molecules dispersed at the threshold concentration for Alzheimer\u2019s disease diagnosis in clinically-relevant volumes of sample. <\/strong><em>J Nanobiotechnology. <\/em>2023 Sep 15;21(1):329. <span style=\"color: #808000;\"><strong><a style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.1186%2Fs12951-023-02095-8\">DOI: 10.1186\/s12951-023-02095-8<\/a><\/strong><\/span>.<\/li>\n<li>Alonso-Alonso ML, Sampedro-Viana A, Rodr\u00edguez-Y\u00e1\u00f1ez M, L\u00f3pez-Dequidt I, Pumar JM, Mosqueira AJ, Fern\u00e1ndez-Rodicio S, Bazarra-Barreiros M, Sobrino T, Campos F, Castillo J, Hervella P, Iglesias-Rey R.<strong> Influence of temperature chronobiology on stroke outcome<\/strong>. <em>Int J Mol Sci.<\/em> 2023 Feb 13;24(4):3746. <span style=\"color: #808000;\"><strong><span class=\"identifier doi\"><span class=\"id-label\">DOI:\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.3390\/ijms24043746\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.3390\/ijms24043746<\/a><\/span><\/strong><\/span><\/li>\n<li>Alonso-Alonso ML, Sampedro-Viana A, Fern\u00e1ndez-Rodicio S, Bazarra-Barreiros M, Ouro A, Sobrino T, Campos F, Castillo J, Hervella P, Iglesias-Rey R. <strong>Need for a paradigm shift in the treatment of cerebrovascular disease: the blood-brain barrier<\/strong>.\u00a0<em>Int J Mol Sci.<\/em> 2022 Aug 22;23(16):9486. <strong><span class=\"identifier doi\" style=\"color: #808000;\"><span class=\"id-label\">DOI:\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.3390\/ijms23169486\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.3390\/ijms23169486<\/a><\/span><\/strong><\/li>\n<li>Alonso-Alonso ML, Perez Mato M, Sampedro-Viana A, Correa-Paz C, Avila-Gomez P, Sobrino T, Campos F,\u00a0Castillo J, Iglesias-Rey R, Hervella P. <strong>Fibrin-Targeted Nanoparticles for Finding, Visualizing and Characterizing Blood Clots in Acute Ischemic Stroke.<\/strong> <em>Pharmaceutics<\/em><strong>. <\/strong>2022 Oct14; (10):2156. <span style=\"color: #808000;\"><strong><span class=\"identifier doi\"><span class=\"id-label\">DOI:\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.3390\/pharmaceutics14102156\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.3390\/pharmaceutics14102156<\/a><\/span><\/strong><\/span><\/li>\n<li>Mishra A, et al.<strong> Stroke genetics informs drug discovery and risk prediction across ancestries<\/strong>. <em>Nature<\/em>. 2022 Sep 30;1-15.\u00a0<span style=\"color: #808000;\"><strong><span class=\"identifier doi\"><span class=\"id-label\">DOI:\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.1038\/s41586-022-05165-3\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.1038\/s41586-022-05165-3<\/a><\/span><\/strong><\/span><\/li>\n<li>C\u00e1rcel-M\u00e1rquez J, et al. <strong>A Polygenic Risk Score Based on a Cardioembolic Stroke Multitrait Analysis Improves a Clinical Prediction Model for This Stroke Subtype<\/strong>. <em>Front Cardiovasc Med<\/em>. 2022 Jul 8; 9:940696. <span style=\"color: #808000;\"><strong><span class=\"identifier doi\"><span class=\"id-label\">DOI:\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.3389\/fcvm.2022.940696\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.3389\/fcvm.2022.940696<\/a><\/span><\/strong><\/span><\/li>\n<li>Alonso-Alonso ML, Sampedro-Viana A, Rodr\u00edguez-Y\u00e1\u00f1ez M, L\u00f3pez-Dequidt I, Pumar JM, J. Mosqueira A, Ouro A, \u00c1vila-G\u00f3mez P, Sobrino T, Campos F,\u00a0Castillo J, Hervella P, Iglesias-Rey R. <strong>Antihyperthermic Treatment in the Management of Malignant Infarction of the Middle Cerebral Artery<\/strong>. <em>Clin. Med<\/em>. 2022 May 19;11(10):2874.\u00a0<span style=\"color: #808000;\"><strong><span class=\"identifier doi\"><span class=\"id-label\">DOI:\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.3390\/jcm11102874\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.3390\/jcm11102874<\/a><\/span><\/strong><\/span><\/li>\n<\/ul>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Group website&#8221; admin_label=&#8221;Web del grupo&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><a href=\"https:\/\/treatneurolab.com\/\">https:\/\/treatneurolab.com\/<\/a><\/p>\n<p>[\/et_pb_toggle][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Investigador\/a l\u00edder&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#10294c&#8221; custom_margin=&#8221;0px||||false|false&#8221; custom_padding=&#8221;6px||0px|6px|false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Lead researcher<\/h2>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;WP Team (cambiar s\u00f3 a ID pola do l\u00edder de equipo)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; locked=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"sp-wp-team-pro-wrapper wp-team-pro-preloader\" >\n\n<div id=\"sptp-10821\" class=\"sp-team-pro sptp-section sptp-new_page pagination_normal sptp-even\" >\n\n\t<div class=\"sp-team-pro-page-loading-image\"><\/div>\n\t<div class=\"sptp-grid\">\n\t\t<div class=\"sptp-row  \">\n\t\t\t\t\t<div class=\"sp-team-pro-item sptp-col-lg-1 sptp-col-md-1 sptp-col-sm-1 sptp-col-xs-1\"\n\t\t\t data-member=\"18826\">\n\t\t\t\t<div class=\"sptp-member  border-bg-around-member sptp-square\">\n\t<a class=\"sptp-member-avatar \"  href=https:\/\/www.idisantiago.es\/en\/team\/francisco-campos-perez\/ target=_blank >\n\t<div class=\"sptp-member-avatar-img-area\" data-id=\"18826\">\n\t\t<div class=\"sptp-member-avatar-img sptp-square sptp-icon-on-image none \">\n\t\t\t<div class=\"sptp-overflow-h\">\n\t\t\t\t\t\t\t\t\t<div class=\"sptp-icon text-center\">\n\t\t\t\t\t<i class=\"fa fa-plus\"><\/i>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" class=\"sptp_default_img\" srcset=\"https:\/\/www.idisantiago.es\/wp-content\/uploads\/2022\/02\/Francisco-Campos-320x320.jpg\" src=\"https:\/\/www.idisantiago.es\/wp-content\/uploads\/2022\/02\/Francisco-Campos-320x320.jpg\" alt=\"Francisco Campos P\u00e9rez\" width=\"320\" height=\"320\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/a>\n\t<div class=\"sptp-member-name \">\n\t\t<h2>\n\t\t\t\t\tFrancisco Campos P\u00e9rez\t\t\t\t<\/h2>\n\t<\/div>\n<div class=\"sptp-member-email\">\n\n<i class=\"fa fa-envelope\"><\/i>\t<a href=\"#0\"  class=\"\">\n\t\t<span>francisco.campos.perez@sergas.es<\/span>\n\t<\/a>\n\t<\/div>\n<div class=\"sptp-member-website\">\n<i class=\"fa fa-globe\"><\/i>\t<a href=\"http:\/\/orcid.org\/0000-0001-8665-1039\"  class=\"\" target=\"_blank\">\n\t\t<span>http:\/\/orcid.org\/0000-0001-8665-1039<\/span>\n\t<\/a>\n\t<\/div>\n<div class=\"sptp-read-more-button\">\n\t<a class=\"sptp-member-read-more-button\" href=\"https:\/\/www.idisantiago.es\/en\/team\/francisco-campos-perez\/\"> + INFO <\/a>\n<\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div> <!-- end row -->\n\t<\/div> <!-- end grid -->\n\t\t\t<\/div>\n<\/div>\n\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00c1REA: NEUROCIENCIASObjectives Study and development of new therapeutic strategies in neuronal pathologies, mainly related to cerebral ischemia. Our perspective is to try that all the knowledge developed in the field [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":16398,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"project_category":[510],"project_tag":[],"class_list":["post-19002","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-neurociencias-en"],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project\/19002","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/types\/project"}],"author":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/comments?post=19002"}],"version-history":[{"count":26,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project\/19002\/revisions"}],"predecessor-version":[{"id":46221,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project\/19002\/revisions\/46221"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/media\/16398"}],"wp:attachment":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/media?parent=19002"}],"wp:term":[{"taxonomy":"project_category","embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project_category?post=19002"},{"taxonomy":"project_tag","embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project_tag?post=19002"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}