{"id":19027,"date":"2022-01-14T13:00:23","date_gmt":"2022-01-14T12:00:23","guid":{"rendered":"https:\/\/www.idisantiago.es\/grupo-de-investigacion\/ac04-endocrinologia-pediatrica\/"},"modified":"2024-07-05T14:26:18","modified_gmt":"2024-07-05T12:26:18","slug":"ac04-endocrinologia-pediatrica","status":"publish","type":"project","link":"https:\/\/www.idisantiago.es\/en\/grupo-de-investigacion\/ac04-endocrinologia-pediatrica\/","title":{"rendered":"AC04 &#8211; Paediatric Endocrinology"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||||false|false&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; custom_padding=&#8221;0px||||false|false&#8221; locked=&#8221;on&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>\u00c1REA: <a href=\"https:\/\/www.idisantiago.es\/areas-de-investigacion\/a003-endocrinologia\/\">ENDOCRINOLOG\u00cdA, NUTRICI\u00d3N Y METABOLISMO<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;2_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.idisantiago.es\/wp-content\/uploads\/2021\/11\/grupo_investigacion.jpg&#8221; title_text=&#8221;Corporate portrait of office workers and employees&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_toggle title=&#8221;Objectives and lines of research&#8221; admin_label=&#8221;Objetivos y l\u00edneas de investigaci\u00f3n&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Objectives<\/h3>\n<ul>\n<li>Study of short stature: Molecular bases and therapeutic alternatives. In the area of \u200b\u200bgrowth, the investigation of the GH-IGF1 hormonal axis and its knowledge from the physiological and genetic point of view, as well as the implications of the molecular alterations of this axis in the therapeutic response, have been of fundamental interest for our group. We are currently working on three aspects within this objective: Idiopathic short stature (TBI). Genetic bases and therapeutic alternatives, study of genes: pituitary transcription factors, GH1, GHR, IGF1, SHOX, FGFR3, NPR2 and their involvement in the etiopathogenesis of short stature and Rasopathies: RAS-MAPK signaling pathway.<\/li>\n<li>Epidemiology and clinical implications of genetic-molecular alterations in endocrine pathology in children. The aspects we work on are: Congenital Adrenal Hyperplasia (CAH), pseudohypoparathyroidism and hypophosphatemic rickets.<\/li>\n<li>Obesity and energy metabolism. Our group has been a pioneer in collaboration with the groups coordinated by Dr. Felipe Casanueva and Dr. Carlos Di\u00e9guez in the study of peptides such as leptin, Ghrelin and adiponectin, among others. It is currently one of the nodes of the RED for the study of the basic mechanisms of body weight homeostasis and the treatment of obesity (RED REGOBE).<\/li>\n<li>Diabetes Mellitus in the pediatric age. The members of our group are involved in the Galician Pediatric Diabetes Mellitus (DM) working group (PEDIAGAL) (research group belonging to the public I+D+I system of Galicia, code 08IDI1648), which encompasses the monitoring of patients in this autonomous community. The studies carried out are aimed at knowing the epidemiological and clinical behavior of Type 1 Diabetes Mellitus in Galicia.\n<p>A study is also being carried out on the atherogenic risk in Galician children with type 1 diabetes mellitus financed by the Xunta de Galicia (file: 10PXIB918023PR) (duration: 2010-2013) on cardiovascular risk factors (degree of adiposity, physical inactivity, atherogenic diet, biochemical alterations and hypertension) of children diagnosed with DM1 in Galicia.<\/li>\n<\/ul>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Research team&#8221; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Equipo investigador&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<table style=\"width: 100%; border-collapse: collapse; border-style: hidden;\" border=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\"><strong>Leader<\/strong><br \/>Castro Feij\u00f3o, Lidia<\/p>\n<p><strong>Members<br \/><\/strong>Barreiro Conde, Jes\u00fas<br \/>Cabanas Rodr\u00edguez, Paloma<br \/>Pombo Arias, Manuel<br \/>Tejera P\u00e9rez, Roberto<br \/>V\u00e1zquez Mato, Mar\u00eda Bego\u00f1a<\/p>\n<p>&nbsp;<\/p>\n<\/td>\n<td style=\"width: 50%;\">\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Projects&#8221; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Proyectos (cambiar s\u00f3 codigo IDIS)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; disabled=&#8221;on&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Publications&#8221; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Publicaciones&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; disabled=&#8221;on&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li>Publicaci\u00f3n 1<\/li>\n<li>Publicaci\u00f3n 2<\/li>\n<li>Etc.<\/li>\n<\/ul>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Group website&#8221; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Web del grupo&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]https:\/\/[\/et_pb_toggle][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Investigador\/a l\u00edder&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#10294c&#8221; custom_margin=&#8221;0px||||false|false&#8221; custom_padding=&#8221;6px||0px|6px|false|false&#8221; locked=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Lead researcher<\/h2>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;WP Team (cambiar s\u00f3 a ID pola do l\u00edder de equipo)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; locked=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<div class=\"sp-wp-team-pro-wrapper wp-team-pro-preloader\" >\n\n<div id=\"sptp-10617\" class=\"sp-team-pro sptp-section sptp-new_page pagination_normal sptp-even\" >\n\n\t<div class=\"sp-team-pro-page-loading-image\"><\/div>\n\t<div class=\"sptp-grid\">\n\t\t<div class=\"sptp-row  \">\n\t\t\t\t\t<div class=\"sp-team-pro-item sptp-col-lg-1 sptp-col-md-1 sptp-col-sm-1 sptp-col-xs-1\"\n\t\t\t data-member=\"18847\">\n\t\t\t\t<div class=\"sptp-member  border-bg-around-member sptp-square\">\n\t<a class=\"sptp-member-avatar \"  href=https:\/\/www.idisantiago.es\/en\/team\/manuel-pombo-arias\/ target=_blank >\n\t<div class=\"sptp-member-avatar-img-area\" data-id=\"18847\">\n\t\t<div class=\"sptp-member-avatar-img sptp-square sptp-icon-on-image none \">\n\t\t\t<div class=\"sptp-overflow-h\">\n\t\t\t\t\t\t\t\t\t<div class=\"sptp-icon text-center\">\n\t\t\t\t\t<i class=\"fa fa-plus\"><\/i>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" class=\"sptp_default_img\" srcset=\"https:\/\/www.idisantiago.es\/wp-content\/plugins\/wp-team-pro\/src\/Frontend\/img\/Placeholder-Image.png\" src=\"https:\/\/www.idisantiago.es\/wp-content\/plugins\/wp-team-pro\/src\/Frontend\/img\/Placeholder-Image.png\" alt=\"Manuel Pombo Arias\" width=\"600\" height=\"450\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/a>\n\t<div class=\"sptp-member-name \">\n\t\t<h2>\n\t\t\t\t\tLidia Castro Feijoo\t\t\t\t<\/h2>\n\t<\/div>\n<div class=\"sptp-read-more-button\">\n\t<a class=\"sptp-member-read-more-button\" href=\"https:\/\/www.idisantiago.es\/en\/team\/manuel-pombo-arias\/\"> + INFO <\/a>\n<\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div> <!-- end row -->\n\t<\/div> <!-- end grid -->\n\t\t\t<\/div>\n<\/div>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00c1REA: ENDOCRINOLOG\u00cdA, NUTRICI\u00d3N Y METABOLISMOObjectives Study of short stature: Molecular bases and therapeutic alternatives. In the area of \u200b\u200bgrowth, the investigation of the GH-IGF1 hormonal axis and its knowledge from [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":10311,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"project_category":[504],"project_tag":[],"class_list":["post-19027","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-endocrinologia-en"],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project\/19027","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/types\/project"}],"author":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/comments?post=19027"}],"version-history":[{"count":13,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project\/19027\/revisions"}],"predecessor-version":[{"id":35036,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project\/19027\/revisions\/35036"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/media\/10311"}],"wp:attachment":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/media?parent=19027"}],"wp:term":[{"taxonomy":"project_category","embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project_category?post=19027"},{"taxonomy":"project_tag","embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project_tag?post=19027"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}