{"id":19031,"date":"2022-01-14T12:21:36","date_gmt":"2022-01-14T11:21:36","guid":{"rendered":"https:\/\/www.idisantiago.es\/grupo-de-investigacion\/e036-celulas-madre-y-enfermedades-humanas\/"},"modified":"2025-06-17T09:07:20","modified_gmt":"2025-06-17T07:07:20","slug":"e036-celulas-madre-y-enfermedades-humanas","status":"publish","type":"project","link":"https:\/\/www.idisantiago.es\/en\/grupo-de-investigacion\/e036-celulas-madre-y-enfermedades-humanas\/","title":{"rendered":"E036 – Stem Cells and Human Diseases"},"content":{"rendered":"

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\u00c1REA: \u00a0GEN\u00c9TICA Y BIOLOG\u00cdA DE SISTEMAS<\/a><\/p>\n

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Objectives<\/h3>\n

The Stem Cells and Human Diseases group has the main objective of contributing to a better understanding of the impact of epigenetic regulation on the transcriptional control of the mammalian genome that governs decisions about the fate of cells during embryonic development and human diseases. . Our most ambitious goal is to develop novel therapeutic strategies for age-related disorders, obesity, and rare diseases. To do this, we use a wide variety of methods in molecular biology, genomic and proteomic approaches, genome editing, and bioinformatics analysis.<\/p>\n

Lines of research<\/h3>\n

The main lines of research in progress of the group are:
1) Modeling of diseases using iPSC technology
2) Discovery of molecular programs involved in cell reprogramming and pluripotency
3) Impact of aging and obesity on epigenetic mechanisms
4) New cell rejuvenation strategies<\/p>\n

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Leader<\/strong>
Fidalgo P\u00e9rez, Miguel \u00c1ngel<\/p>\n

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Members<\/strong>
Ameneiro Qui\u00f1oy, Cristina
Escudero P\u00e9rez, Adriana
Fuentes Iglesias, Alejandro
Garc\u00eda Outeiral, Vera
Pardavila Paz, Jos\u00e9 \u00c1ngel<\/p>\n<\/td>\n

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