{"id":19050,"date":"2022-01-14T10:49:55","date_gmt":"2022-01-14T09:49:55","guid":{"rendered":"https:\/\/www.idisantiago.es\/grupo-de-investigacion\/c030-oncologia-medica-traslacional\/"},"modified":"2026-03-04T11:51:49","modified_gmt":"2026-03-04T10:51:49","slug":"c030-oncologia-medica-traslacional","status":"publish","type":"project","link":"https:\/\/www.idisantiago.es\/en\/grupo-de-investigacion\/c030-oncologia-medica-traslacional\/","title":{"rendered":"C030 &#8211; Translational Medical Oncology"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||||false|false&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; custom_padding=&#8221;0px||||false|false&#8221; locked=&#8221;on&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>\u00c1REA: <a href=\"https:\/\/www.idisantiago.es\/en\/research-areas-2\/a001-oncologia\/\">ONCOLOG\u00cdA<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;2_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.idisantiago.es\/wp-content\/uploads\/2021\/11\/grupo_investigacion.jpg&#8221; title_text=&#8221;Corporate portrait of office workers and employees&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_toggle title=&#8221;Objectives and lines of research&#8221; admin_label=&#8221;Objetivos y l\u00edneas de investigaci\u00f3n&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Objectives<\/h3>\n<p>The Medical Oncology Service seeks to integrate care, research and teaching in the day-to-day work of all its members and in all its actions, present and future, with a collaborative vocation with other groups of IDIS, Sergas, the University and national and international with the ultimate mission of knowing and curing cancer. In research, clinical and translational research stands out. Currently we have 70 open clinical trials from phase I to phase IV, promoted by Pharmaceutical Companies, National and International Cooperative Groups and non-commercial research, in most tumor pathologies.<\/p>\n<h3>Lines of research<\/h3>\n<p>Translational research has as its main objective the metastasis process that aims to fully integrate research work into healthcare, and the ambitious commitment that research results feed the Clinical Trials Program and vice versa. The lines are:<\/p>\n<ul>\n<li>Liquid biopsy with the characterization and clinical value of Circulating Tumor Cells (CTC) and other blood products<\/li>\n<li>Invasion and metastasis: both the characterization of these mechanisms and their relationship with the biology of CTCs and the epithelial-mesenchymal transition are focused.<\/li>\n<li>Epigenetics (mainly methylation) in brain and pancreatic tumors<\/li>\n<li>New screening and modeling strategies in oncology: in close collaboration with the IDIS group led by Laura S\u00e1nchez, we are developing and applying the zebrafish animal model in oncology, both as a model for studying processes related to metastasis, and as a screening and application model<\/li>\n<li>Nanotechnology applied in oncology: in 2013 we created the nano-oncology laboratory, where we integrate nanotechnology for the development of new therapeutic strategies and diagnostic agents (nanotheranostics). There is also close collaboration with the IDIS NANOBIOFAR group led by Mar\u00eda Jos\u00e9 Alonso<\/li>\n<\/ul>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Research team&#8221; admin_label=&#8221;Equipo investigador&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p><strong>Leader<\/strong><br \/>L\u00f3pez L\u00f3pez, Rafael<\/p>\n<p>&nbsp;<\/p>\n<table style=\"width: 100.58%; border-collapse: collapse; border-style: hidden; height: 839px;\" border=\"0\">\n<tbody>\n<tr style=\"height: 839px;\">\n<td style=\"width: 48.2975%; height: 839px;\"><strong>Members<\/strong><br \/>Abal Posada, Miguel<br \/>Abalo Pi\u00f1eiro, Alicia<br \/>Abuelo Rey, Jos\u00e9 Manuel<br \/>Abu\u00edn Redondo, Carmen<br \/>Agu\u00edn Losada, Santiago<br \/>\u00c1lvarez Fern\u00e1ndez, Javier<br \/>Anido Herranz, Urbano<br \/>Ant\u00f3n Cameselle, Abraham<br \/>Arias D\u00edaz, Andrea Estrella<br \/>Aybar Molina, Mar\u00eda Isabel<br \/>Barbaz\u00e1n Garc\u00eda, Jorge<br \/>Barbero Mart\u00ednez, Mar\u00eda<br \/>Betancor Rivero, Yoel Zacar\u00edas<br \/>Blanco Freire, Cristina<br \/>Brozos V\u00e1zquez, Elena<br \/>Candamio Folgar, Sonia Mar\u00eda<br \/>Carmona Campos, Marta<br \/>Clemente de la Torre, Carlota<br \/>Cortegoso Mosquera, Alexandra<br \/>Costa Fraga, Nicol\u00e1s<br \/>Costa Nogueira, Clotilde<br \/>Cueva Ba\u00f1uelos, Juan Fernando<br \/>Curiel Garc\u00eda, Mar\u00eda Teresa<br \/>D\u00e1vila Ib\u00e1\u00f1ez, Ana Bel\u00e9n<br \/>D\u00edaz Lagares, \u00c1ngel<br \/>Diez Grand\u00edo, Mar\u00eda Isabel<br \/>Dubbelman Vizca\u00edno, Jaime<br \/>Fern\u00e1ndez D\u00edaz, Natalia<br \/>Fern\u00e1ndez Nogueira, Manuel<br \/>Fern\u00e1ndez Reino, Candela<br \/>Fern\u00e1ndez Santiago, Crist\u00f3bal<br \/>Ferreiro Migu\u00e9ns, Roc\u00edo<br \/>Freijido \u00c1lvarez, Pablo<br \/>Fuentes Varela, Laura<br \/>Garc\u00eda Gonz\u00e1lez, Jorge Jos\u00e9<br \/>Garc\u00eda L\u00f3pez, Gloria<br \/>Garc\u00eda Mart\u00ednez, Carolina<br \/>Garc\u00eda Rub\u00edn, Silvia<br \/>Garrido Ceacero, Raquel<br \/>Gir\u00e1ldez Mart\u00ednez, Mart\u00edn<br \/>G\u00f3mez Garc\u00eda, Mar\u00eda de los \u00c1ngeles<br \/>G\u00f3mez Valencia, Cristina<br \/>Huesa Carballo, Claudia Betsab\u00e9<br \/>Lago Lest\u00f3n, Ram\u00f3n Manuel<br \/>Le\u00f3n Mateos, Luis \u00c1ngel<br \/>Lombard\u00eda Rodr\u00edguez, Helena<br \/>L\u00f3pez Landrove, Sonia<\/td>\n<td style=\"width: 51.7025%; height: 839px;\">L\u00f3pez Rodr\u00edguez, Rosa<br \/>Mart\u00ednez Lago, Nieves Purificaci\u00f3n<br \/>M\u00e9ndez Barrio, Estiban<br \/>Mondelo Mac\u00eda, Patricia<br \/>Muinelo Romay, Laura<br \/>Palacios Ozores, Patricia<br \/>Paredes Cotor\u00e9, Jes\u00fas Pedro<br \/>Pi\u00f1eiro Cid, Roberto<br \/>Pi\u00f1eiro P\u00e9rez, Raquel<br \/>Pita L\u00f3pez, Pablo<br \/>Portos Conde, Iria<br \/>Rapado Gonz\u00e1lez, \u00d3scar<br \/>Rivas Limeres, Ver\u00f3nica<br \/>Roca Mart\u00ednez, Carlota<br \/>Rodr\u00edguez L\u00f3pez, Carmela<br \/>Rodr\u00edguez Mart\u00ednez, Natalia<br \/>Rodr\u00edguez P\u00e9rez, Manuel<br \/>Rodr\u00edguez Poci\u00f1a, Luc\u00eda<br \/>Rubal Otero, Lara<br \/>Ruiz Ba\u00f1obre, Juan<br \/>Su\u00e1rez Cunqueiro, Mar\u00eda Mercedes<br \/>Su\u00e1rez Dono, Francisco Javier<br \/>Torres Losada, Ana<br \/>Tu\u00f1as P\u00e9rez, Joel<br \/>Vali\u00f1a Amado, Laura<br \/>Varela Pose, Vanesa<br \/>Vidal Insua, Yolanda<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><strong>External Collaborator Staff<\/strong><br \/>Cernadas Pazos, Aroa<br \/>Gago Fuentes, Raquel<br \/>Lago Baameiro, Nerea<br \/>Lorenzo G\u00f3mez, Irene<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Proyectos&#8221; 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_builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Investigador\/a l\u00edder&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#10294c&#8221; custom_margin=&#8221;0px||||false|false&#8221; custom_padding=&#8221;6px||0px|6px|false|false&#8221; locked=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Investigador l\u00edder<\/h2>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;WP Team (cambiar s\u00f3 a ID pola do l\u00edder de equipo)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; locked=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"sp-wp-team-pro-wrapper wp-team-pro-preloader\" >\n\n<div id=\"sptp-10461\" class=\"sp-team-pro sptp-section sptp-new_page pagination_normal sptp-even\" >\n\n\t<div class=\"sp-team-pro-page-loading-image\"><\/div>\n\t<div class=\"sptp-grid\">\n\t\t<div class=\"sptp-row  \">\n\t\t\t\t\t<div class=\"sp-team-pro-item sptp-col-lg-1 sptp-col-md-1 sptp-col-sm-1 sptp-col-xs-1\"\n\t\t\t data-member=\"12311\">\n\t\t\t\t<div class=\"sptp-member  border-bg-around-member sptp-square\">\n\t<a class=\"sptp-member-avatar \"  href=https:\/\/www.idisantiago.es\/en\/team\/rafael-lopez-lopez\/ target=_blank >\n\t<div class=\"sptp-member-avatar-img-area\" data-id=\"12311\">\n\t\t<div class=\"sptp-member-avatar-img sptp-square sptp-icon-on-image none \">\n\t\t\t<div class=\"sptp-overflow-h\">\n\t\t\t\t\t\t\t\t\t<div class=\"sptp-icon text-center\">\n\t\t\t\t\t<i class=\"fa fa-plus\"><\/i>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" class=\"sptp_default_img\" srcset=\"https:\/\/www.idisantiago.es\/wp-content\/uploads\/2021\/11\/rafaellopezlopez.jpg\" src=\"https:\/\/www.idisantiago.es\/wp-content\/uploads\/2021\/11\/rafaellopezlopez.jpg\" alt=\"Rafael L\u00f3pez L\u00f3pez\" width=\"320\" height=\"320\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/a>\n\t<div class=\"sptp-member-name \">\n\t\t<h2>\n\t\t\t\t\tRafael L\u00f3pez L\u00f3pez\t\t\t\t<\/h2>\n\t<\/div>\n<div class=\"sptp-member-email\">\n\n<i class=\"fa fa-envelope\"><\/i>\t<a href=\"#0\"  class=\"\">\n\t\t<span>rafael.lopez.lopez@sergas.es<\/span>\n\t<\/a>\n\t<\/div>\n<div class=\"sptp-read-more-button\">\n\t<a class=\"sptp-member-read-more-button\" href=\"https:\/\/www.idisantiago.es\/en\/team\/rafael-lopez-lopez\/\"> + INFO <\/a>\n<\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div> <!-- end row -->\n\t<\/div> <!-- end grid -->\n\t\t\t<\/div>\n<\/div>\n\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00c1REA: ONCOLOG\u00cdAObjectives The Medical Oncology Service seeks to integrate care, research and teaching in the day-to-day work of all its members and in all its actions, present and future, with [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":15719,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"project_category":[512],"project_tag":[],"class_list":["post-19050","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-oncologia-en"],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project\/19050","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/types\/project"}],"author":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/comments?post=19050"}],"version-history":[{"count":59,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project\/19050\/revisions"}],"predecessor-version":[{"id":45450,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project\/19050\/revisions\/45450"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/media\/15719"}],"wp:attachment":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/media?parent=19050"}],"wp:term":[{"taxonomy":"project_category","embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project_category?post=19050"},{"taxonomy":"project_tag","embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project_tag?post=19050"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}