{"id":27556,"date":"2023-03-23T14:19:24","date_gmt":"2023-03-23T13:19:24","guid":{"rendered":"https:\/\/www.idisantiago.es\/?post_type=project&p=27556"},"modified":"2026-02-25T13:55:30","modified_gmt":"2026-02-25T12:55:30","slug":"e060-computational-and-genomic-hematology-grheco-xen","status":"publish","type":"project","link":"https:\/\/www.idisantiago.es\/en\/grupo-de-investigacion\/e060-computational-and-genomic-hematology-grheco-xen\/","title":{"rendered":"E060 -Computational and genomic hematology (Grheco Xen)"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.16″ _module_preset=”default” custom_padding=”0px||||false|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.16″ _module_preset=”default” width=”100%” custom_padding=”0px||||false|false” locked=”off” collapsed=”off” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.17.0″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

\u00c1REA: \u00a0ONCOLOGY<\/a><\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”2_3,1_3″ _builder_version=”4.16″ _module_preset=”default” width=”100%” global_colors_info=”{}”][et_pb_column type=”2_3″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.idisantiago.es\/wp-content\/uploads\/2023\/04\/IMG-20210323-WA0036.jpg” alt=”Grupo E060″ title_text=”IMG-20210323-WA0036″ disabled_on=”off|off|off” _builder_version=”4.19.4″ _module_preset=”default” global_colors_info=”{}”][\/et_pb_image][et_pb_toggle title=”Objectives and lines of research” disabled_on=”off|off|off” admin_label=”Objetivos y l\u00edneas de investigaci\u00f3n” _builder_version=”4.19.4″ _module_preset=”default” body_font=”|300|||||||” global_colors_info=”{}”]<\/p>\n

Objectives<\/h3>\n

This research group has focused on the application of advanced information technologies in the field of oncohaematological tumors. These approaches, reflected in the diversity of our research, have focused on the following main objectives:<\/p>\n

1. Identification of genes that drive oncogenesis and tumor progression in hematological malignancies.
2. Identification of recurrently altered signaling pathways in the genome of hematological tumors.
3. Development of machine learning prognostic models in different types of oncohaematological malignancies based on clinical and molecular information
4. Development of predictive models of response to drugs or drug combinations based on the integration of molecular and clinical variables.<\/p>\n

Lines of research<\/h3>\n

1. Development of new prognostic models based on data from national and international collaborative groups.
2. Standardization of clinical and molecular models to improve risk stratification of patients with hematologic malignancies, particularly lymphomas, myelomas, and myeloid malignancies.
3. Development of new scores to predict the response to drugs in clinical trials.
4. Creation of new computer vision systems (computer vision) to infer prognostic patterns based on deep neural networks and learning transfer.
5. Optimization of preclinical drug development using computational tools, including machine learning models.<\/p>\n

 <\/p>\n

[\/et_pb_toggle][et_pb_toggle title=”Research team” admin_label=”Equipo investigador” _builder_version=”4.21.0″ _module_preset=”default” body_font=”|300|||||||” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Leader<\/strong>
Mosquera Orgueira, Adri\u00e1n<\/p>\n\n\n\n
Members<\/strong>
Abal Garc\u00eda, Rosanna
Abu\u00edn M\u00e9ndez, Isabel Mar\u00eda
Alarc\u00f3n Veleiro, Carmen F\u00e1tima
Bao P\u00e9rez, Laura
Chieochansin, Thaweesak
Crucitti, Davide
Dasilva Freire, Noelia
del Olmo Linares, Marco
D\u00edaz Arias, Jos\u00e9 \u00c1ngel
Fern\u00e1ndez Mellid, Eugenia
Ferreiro Ferro, Roi
Ferreiro Pant\u00edn, Miriam<\/td>\n		Lorente Berm\u00fadez, Roberto
P\u00e9rez M\u00edguez, Carlos
Pi\u00f1eiro Fiel, Manuel
Portela Pi\u00f1eiro, V\u00edctor
Regueiro Garc\u00eda, Alexandra
Rojas Mart\u00ednez, Javier Alberto
Soto Carracedo, Sara
Tarr\u00edo P\u00e9rez, Ana
Vilari\u00f1o L\u00f3pez, Mar\u00eda Dolores
Wantoch, \u0141ukasz<\/p>\n

 <\/p>\n

External Collaborator Staff<\/strong>
Calvi\u00f1o Su\u00e1rez, Michael
Riera T\u00e1boas, Ana
Rodr\u00edguez L\u00f3pez, Manuel<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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[\/et_pb_toggle][et_pb_toggle title=”Publications” disabled_on=”off|off|off” admin_label=”Publicaciones” _builder_version=”4.21.0″ _module_preset=”default” body_font=”|300|||||||” global_colors_info=”{}”]<\/p>\n