{"id":46303,"date":"2025-12-05T11:31:53","date_gmt":"2025-12-05T10:31:53","guid":{"rendered":"https:\/\/www.idisantiago.es\/grupo-de-investigacion\/neurohula\/"},"modified":"2026-04-15T13:40:34","modified_gmt":"2026-04-15T11:40:34","slug":"neurohula","status":"publish","type":"project","link":"https:\/\/www.idisantiago.es\/en\/grupo-de-investigacion\/neurohula\/","title":{"rendered":"HULA &#8211; NeuroHULA"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||||false|false&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; custom_padding=&#8221;0px||||false|false&#8221; locked=&#8221;off&#8221; collapsed=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"https:\/\/www.idisantiago.es\/en\/grupos-de-investigacion\/\"><strong>RESARCH GROUP<\/strong><\/a><\/p>\n<h1>HULA &#8211; NeuroHULA<\/h1>\n<p>&nbsp;<\/p>\n<p>CATEGOR\u00cdA: <span style=\"color: #003366;\">GRUPOS COLABORADORES<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;2_3,1_3&#8243; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image title_text=&#8221;IMG-20230418-WA0000&#8243; disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_toggle title=&#8221;Objectives and lines of research&#8221; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Objetivos y l\u00edneas de investigaci\u00f3n&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3><span class=\"Y2IQFc\" lang=\"en\">Objectives<\/span><\/h3>\n<p><span class=\"Y2IQFc\" lang=\"en\">To study potential diagnostic and therapeutic strategies for neurological diseases for their future use in routine clinical practice<\/span>.<\/p>\n<h3><span class=\"Y2IQFc\" lang=\"en\">Lines of research<\/span><\/h3>\n<ul>\n<li><span class=\"Y2IQFc\" lang=\"en\">Early diagnosis, biomarkers, and treatment of Alzheimer&#8217;s disease and other dementia<\/span>.<\/li>\n<li><span class=\"Y2IQFc\" lang=\"en\">Diagnostic and prognostic biomarkers of cerebrovascular disease<\/span>.<\/li>\n<li><span class=\"Y2IQFc\" lang=\"en\">Diagnosis, biomarkers, and treatment of epilepsy<\/span>.<\/li>\n<li><span class=\"Y2IQFc\" lang=\"en\">Biomarkers, diagnosis, and treatment of multiple sclerosis<\/span>.<\/li>\n<li><span class=\"Y2IQFc\" lang=\"en\">Biomarkers, diagnosis, and treatment of migraine<\/span>.<\/li>\n<\/ul>\n<pre id=\"tw-target-text\" class=\"tw-data-text tw-text-large tw-ta\" dir=\"ltr\" tabindex=\"-1\" role=\"text\" data-placeholder=\"Traducci\u00f3n\" data-ved=\"2ahUKEwiO2oz63uqTAxUH1AIHHehLNwEQ3ewLegQIDBAV\" aria-label=\"Texto traducido: Objectives To study potential diagnostic and therapeutic strategies for neurological diseases for their future use in routine clinical practice. Research Areas Early diagnosis, biomarkers, and treatment of Alzheimer's disease and other dementias. Diagnostic and prognostic biomarkers of cerebrovascular disease. Diagnosis, biomarkers, and treatment of epilepsy. Biomarkers, diagnosis, and treatment of multiple sclerosis. Biomarkers, diagnosis, and treatment of migraine.\">\u00a0<\/pre>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Research team&#8221; admin_label=&#8221;Equipo investigador&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<table style=\"width: 100%; border-collapse: collapse; border-style: hidden;\" border=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\">\n<p><strong>Leader<\/strong><br \/>Pego Reigosa, Robustiano<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Members<\/strong><br \/>Bermello L\u00f3pez, Lourdes<br \/>Corredoira L\u00f3pez, Sara<br \/>Fern\u00e1ndez Cabrera, Alejandro<br \/>Figueira G\u00f3mez, Ant\u00eda<br \/>Rodr\u00edguez Ares, Tania<br \/>V\u00e1zquez L\u00f3pez, Esther<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<\/td>\n<td style=\"width: 50%;\">\u00a0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Projects&#8221; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Proyectos (cambiar s\u00f3 codigo IDIS)&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Estudio Observacional para evaluar el cumplimiento terap\u00e9utico de los pacientes con esclerosis m\u00faltiple en tratamiento con terapias modificadoras de la enfermedad de primera l\u00ednea. Estudio Compliance. E-0232. NOV-TME-2010-01.<br \/>Estudio de biomarcadores en LCR para el diagn\u00f3stico de EA prodr\u00f3mica en pacientes con deterioro cognitivo ligero. Estudio PREDEM. ENOSM\/2012\/01. NOV-SNC-2011-01.<br \/>Estudio observacional, prospectivo, multinacional, multic\u00e9ntrico, que compara la efectividad de Safinamida, Rasagilina y otros \u201ctratamientos est\u00e1ndar\u201d como tratamiento complementario a la levodopa (L-dopa) en pacientes con enfermedad de Parkinson (EP) fluctuante. E-2203. Z7219N04 (ZAM-SAF-2019-01).<\/p>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Publications&#8221; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Publicaciones&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li>R Pego-Reigosa, S L\u00f3pez-L\u00f3pez, ME V\u00e1zquez-L\u00f3pez, V Armesto-P\u00e9rez, F Bra\u00f1as-Fern\u00e1ndez, F Mart\u00ednez-V\u00e1zquez, R Pi\u00f1eiro-Bola\u00f1o, JA Cort\u00e9s-La\u00ed\u00f1o. <strong>Sea wave-induced internal carotid artery dissection<\/strong>. <em>Neurology<\/em> 2005 Jun 14; 64(11):1980. <span class=\"identifier doi\"><span class=\"id-label\">: <span style=\"color: #808000;\"><strong>doi: <\/strong><\/span><\/span><span style=\"color: #808000;\"><strong><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.1212\/01.wnl.0000163855.78628.42\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.1212\/01.WNL.0000163855.78628.42<\/a><\/strong><\/span><\/span><\/li>\n<li>Pego-Reigosa R, V\u00e1zquez-L\u00f3pez ME, Iglesias-G\u00f3mez S, Martinez-V\u00e1zquez F. <strong>Association between chronic paroxysmal hemicrania and primary trochlear headache: pathophysiology and treatment<\/strong>. <em>Cephalalgia<\/em> 2006; 26 (10): 1252-1254. <span style=\"color: #808000;\"><strong>doi<span class=\"identifier doi\"><span class=\"id-label\">:\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.1111\/j.1468-2982.2006.01202.x\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.1111\/j.1468-2982.2006.01202.x<\/a><\/span><\/strong><\/span><\/li>\n<li>Mu\u00f1oz D, Escart\u00edn A, Dapena D, Coret F, Fern\u00e1ndez-Ur\u00eda D, P\u00e9rez D, Casanova B, Guijarro-Castro C, Munteis E, del-Campo Amigo M, Pego R, Calles C, Garc\u00eda-Rey C, Monsalve N, S\u00e1nchez-Matienzo D. <strong>Adverse events during the titration phase of interferon-beta in remitting-relapsing multiple sclerosis are not predicted by body mass index nor by pharmacodynamic biomarkers<\/strong>. <em>BMC Neurol<\/em>. 2013 Jul 11;13 :82. <strong><span style=\"color: #808000;\">doi<span class=\"identifier doi\"><span class=\"id-label\">: <\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.1186\/1471-2377-13-82\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.1186\/1471-2377-13-82<\/a><\/span><\/span><\/strong><\/li>\n<li>Alberte-Woodward M, da Silva-Fran\u00e7a CF, Rodr\u00edguez-Gay I, Pego-Reigosa R. <strong>Safety of Intravenous Thrombolysis for Acute Stroke in Patients with an Active Malignancy: Case Series and Review of the Literature<\/strong>. <em>Eur Neurol.<\/em> 2019;81(3-4): 163-166.<\/li>\n<li>Fern\u00e1ndez-Cabrera A, Garc\u00eda-De Soto J, Pego-Reigosa R, Su\u00e1rez-Quintanilla J. <strong>Relationship between periodontitis and cerebral atrophy: A cross-sectional study.<\/strong> <em>Dent Med Probl.<\/em> 2025 May-Jun;62(3): 493-498.<\/li>\n<li>Garc\u00eda-de Soto J, Castro-Mosquera M, Pouso-Diz JM, Fern\u00e1ndez-Cabrera A, Rodr\u00edguez-Arrizabalaga M, Debasa-Mouce M, Camino-Casti\u00f1eiras J, Minguill\u00f3n Pereiro AM,<\/li>\n<li>Aramburu-N\u00fa\u00f1ez M, Romaus-Sanjurjo D, Aldrey JM, Pego-Reigosa R, P\u00edas-Peleteiro JM, Sobrino T, Ouro A. <strong>Unraveling the Role of Autotaxin and Lysophosphatidic Acid in Alzheimer&#8217;s Disease: From Molecular Mechanisms to Therapeutic Potential.<\/strong> <em>Int J Mol Sci.<\/em> 2025 Jul 23;26(15): 7068.<\/li>\n<li>Fern\u00e1ndez-Cabrera A, Santamar\u00eda-Montero P, Garc\u00eda de-Soto J, Pego-Reigosa R. <strong>MonoPER study: Effectiveness and tolerability of PERampanel in monotherapy in real-world after 12 months of treatment.<\/strong> <em>Epilepsia Open<\/em>. 2025 Oct;10(5): 1587-1594.<\/li>\n<li>Fern\u00e1ndez-Cabrera A, Santamar\u00eda-Montero P, Soto JG, Figueira-G\u00f3mez A, Rodr\u00edguez-Botana M, P\u00e9rez-Regojo B, Pego-Reigosa R. <strong>EPIDEP: Prevalence of undiagnosed depression in an epilepsy outpatient clinic.<\/strong> <em>Epilepsy Behav Rep.<\/em> 2025 Aug 9;32:100819.<\/li>\n<\/ul>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Web del grupo&#8221; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Web del grupo&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>https:\/\/<\/p>\n<p>[\/et_pb_toggle][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Investigador\/a l\u00edder&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#10294c&#8221; custom_margin=&#8221;0px||||false|false&#8221; custom_padding=&#8221;6px||0px|6px|false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Investigador l\u00edder<\/h2>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;WP Team (cambiar s\u00f3 a ID pola do l\u00edder de equipo)&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<div class=\"sp-wp-team-pro-wrapper wp-team-pro-preloader\" >\n\n<div id=\"sptp-43607\" class=\"sp-team-pro sptp-section sptp-new_page pagination_normal sptp-even\" >\n\n\t<div class=\"sp-team-pro-page-loading-image\"><\/div>\n\t<div class=\"sptp-grid\">\n\t\t<div class=\"sptp-row  \">\n\t\t\t\t\t<div class=\"sp-team-pro-item sptp-col-lg-1 sptp-col-md-1 sptp-col-sm-1 sptp-col-xs-1\"\n\t\t\t data-member=\"43599\">\n\t\t\t\t<div class=\"sptp-member  border-bg-around-member sptp-square\">\n\t<a class=\"sptp-member-avatar \"  href=https:\/\/www.idisantiago.es\/en\/team\/43599\/ target=_blank >\n\t<div class=\"sptp-member-avatar-img-area\" data-id=\"43599\">\n\t\t<div class=\"sptp-member-avatar-img sptp-square sptp-icon-on-image none \">\n\t\t\t<div class=\"sptp-overflow-h\">\n\t\t\t\t\t\t\t\t\t<div class=\"sptp-icon text-center\">\n\t\t\t\t\t<i class=\"fa fa-plus\"><\/i>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" class=\"sptp_default_img\" srcset=\"https:\/\/www.idisantiago.es\/wp-content\/uploads\/2025\/12\/Pego-320x320.jpg\" src=\"https:\/\/www.idisantiago.es\/wp-content\/uploads\/2025\/12\/Pego-320x320.jpg\" alt=\"Robustiano Pego Reigosa\" width=\"320\" height=\"320\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/a>\n\t<div class=\"sptp-member-name \">\n\t\t<h2>\n\t\t\t\t\tRobustiano Pego Reigosa\t\t\t\t<\/h2>\n\t<\/div>\n<div class=\"sptp-member-email\">\n\n<i class=\"fa fa-envelope\"><\/i>\t<a href=\"#0\"  class=\"\">\n\t\t<span>robustiano.pego.reigosa@sergas.es<\/span>\n\t<\/a>\n\t<\/div>\n<div class=\"sptp-member-phone\">\n<i class=\"fa fa-phone\"><\/i>\t<a href=\"#0\"  class=\"\" >\n\t\t<span>982296698<\/span>\n\t<\/a>\n\t<\/div>\n<div class=\"sptp-read-more-button\">\n\t<a class=\"sptp-member-read-more-button\" href=\"https:\/\/www.idisantiago.es\/en\/team\/43599\/\"> + INFO <\/a>\n<\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div> <!-- end row -->\n\t<\/div> <!-- end grid -->\n\t\t\t<\/div>\n<\/div>\n\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; RESARCH GROUP HULA &#8211; NeuroHULA &nbsp; CATEGOR\u00cdA: GRUPOS COLABORADORESObjectives To study potential diagnostic and therapeutic strategies for neurological diseases for their future use in routine clinical practice. Lines of [&hellip;]<\/p>\n","protected":false},"author":14,"featured_media":10311,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"project_category":[890],"project_tag":[],"class_list":["post-46303","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-collaborating-groups"],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project\/46303","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/types\/project"}],"author":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/comments?post=46303"}],"version-history":[{"count":7,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project\/46303\/revisions"}],"predecessor-version":[{"id":46461,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project\/46303\/revisions\/46461"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/media\/10311"}],"wp:attachment":[{"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/media?parent=46303"}],"wp:term":[{"taxonomy":"project_category","embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project_category?post=46303"},{"taxonomy":"project_tag","embeddable":true,"href":"https:\/\/www.idisantiago.es\/en\/wp-json\/wp\/v2\/project_tag?post=46303"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}