{"id":16653,"date":"2022-03-15T13:01:47","date_gmt":"2022-03-15T12:01:47","guid":{"rendered":"https:\/\/www.idisantiago.es\/grupo-de-investigacion\/ac04-endocrinoloxia-pediatrica\/"},"modified":"2026-09-21T11:57:09","modified_gmt":"2026-09-21T09:57:09","slug":"ac04-endocrinoloxia-pediatrica","status":"publish","type":"project","link":"https:\/\/www.idisantiago.es\/gl\/grupo-de-investigacion\/ac04-endocrinoloxia-pediatrica\/","title":{"rendered":"AC04 &#8211; Endocrinolox\u00eda Pedi\u00e1trica"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||||false|false&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; custom_padding=&#8221;0px||||false|false&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>\u00c1REA: <a href=\"https:\/\/www.idisantiago.es\/gl\/areas-de-investigacion\/a003-endocrinologia\/\">ENDOCRINOLOX\u00cdA<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;2_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.idisantiago.es\/wp-content\/uploads\/2021\/11\/grupo_investigacion.jpg&#8221; title_text=&#8221;Corporate portrait of office workers and employees&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_toggle title=&#8221;Obxectivos e li\u00f1as de investigaci\u00f3n&#8221; admin_label=&#8221;Objetivos y l\u00edneas de investigaci\u00f3n&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Obxectivos<\/h3>\n<ul>\n<li>Estudo da talla baixa: Bases moleculares e alternativas terap\u00e9uticas. Na \u00e1rea de crecemento \u00e9 interese fundamental para o noso grupo a investigaci\u00f3n do eixe hormonal GH- IGF1 e o seu co\u00f1ecemento dende o punto de vista fisiol\u00f3xico e xen\u00e9tico, as\u00ed como as implicaci\u00f3ns das alteraci\u00f3ns moleculares deste eixe na resposta terap\u00e9utica. Actualmente estamos traballando en tres aspectos dentro deste obxectivo: Talla baia idiop\u00e1tica (TBI). Bases xen\u00e9ticas e alternativas terap\u00e9uticas, estudo dos xenes: factores de transcrici\u00f3n hipofisarios, GH1, GHR, IGF1, SHOX, FGFR3, NPR2 e a s\u00faa implicaci\u00f3n na etiopatoxenia da talla baixa e Rasopat\u00edas: v\u00eda de sinalizaci\u00f3n RAS-MAPK.<\/li>\n<li>Epidemiolox\u00eda e implicaci\u00f3ns cl\u00ednicas das alteraci\u00f3ns xen\u00e9tico-moleculares na patolox\u00eda endocrina do neno. Os aspectos sobre os que traballamos son: Hiperplasia Suprarrenal Conx\u00e9nita (HSC), pseudohipoparatiroidismo e raquitismo hipofosfat\u00e9mico.<\/li>\n<li>Obesidade e metabolismo enerx\u00e9tico. O noso grupo foi pioneiro en colaboraci\u00f3n cos grupos coordinados polo Dr. Felipe Casanueva e Dr. Carlos Di\u00e9guez no estudo de p\u00e9ptidos como leptina, Ghrelin e adiponectina, entre outros. Actualmente \u00e9 un dos nodos da RED para o estudo dos mecanismos b\u00e1sicos da homeostase do peso corporal e o tratamento da obesidade (RED REGOBE).<\/li>\n<li>Diabete Mellitus na idade pedi\u00e1trica. Os membros do noso grupo est\u00e1n implicados no grupo de traballo de Diabete Mellitus (DM) na idade pedi\u00e1trica de Galicia (PEDIAGAL) (grupo de investigaci\u00f3n pertencente \u00f3 sistema p\u00fablico I+D+I de Galicia, c\u00f3digo 08IDI1648), que engloba o seguimento dos pacientes desta comunidade aut\u00f3noma. Os estudos efectuados est\u00e1n orientados a co\u00f1ecer o comportamento epidemiol\u00f3xico e cl\u00ednico da Diabete Mellitus tipo 1 en Galicia.<\/li>\n<\/ul>\n<p>Tam\u00e9n se est\u00e1 efectuando un estudo sobre o risco aterox\u00e9nico en nenos galegos con diabete mellitus tipo 1 financiado pola Xunta de Galicia (expediente: 10PXIB918023PR) (duraci\u00f3n: 2010-2013) sobre os factores de risco cardiovascular (grado de adiposidade, inactividade f\u00edsica, dieta aterox\u00e9nica, alteraci\u00f3ns bioqu\u00edmicas e HTA) dos nenos diagnosticados de DM1 en Galicia.<\/p>\n<p>&nbsp;[\/et_pb_toggle][et_pb_toggle title=&#8221;Equipo investigador&#8221; disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Equipo investigador&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p><strong>L\u00edder<\/strong><br \/>Castro Feij\u00f3o, Lidia<\/p>\n<p><strong>Membros<\/strong><br \/>Cabanas Rodr\u00edguez, Paloma<br \/>Tejera P\u00e9rez, Roberto<\/p>\n<p><strong>Persoal Colaborador Externo<\/strong><br \/>Barreiro Conde, Jes\u00fas<br \/>Pombo Arias, Manuel<\/p>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Proxectos&#8221; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Proyectos (cambiar s\u00f3 codigo IDIS)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; disabled=&#8221;on&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Publicaci\u00f3ns&#8221; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Publicaciones&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; disabled=&#8221;on&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li>Publicaci\u00f3n 1<\/li>\n<li>Publicaci\u00f3n 2<\/li>\n<li>Etc.<\/li>\n<\/ul>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Web do grupo&#8221; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Web del grupo&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>https:\/\/<\/p>\n<p>[\/et_pb_toggle][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text disabled_on=&#8221;off|off|off&#8221; admin_label=&#8221;Investigador\/a l\u00edder&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#10294c&#8221; 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.sptp-arrow, .sptp-mosaic .sptp-col-lg-4.sptp-member:nth-child(8n-2) .sptp-arrow, .sptp-mosaic .sptp-col-lg-4.sptp-member:nth-child(8n-3) .sptp-arrow { left: auto; right: -20px; border-left-width: 20px; border-right-width: 0; } }div, h2, h4,.sptp-member-name-title { font-family: 'Roboto'; } #sptp-7994 .sptp-member-name .sptp-member-name-title{ color:#8A7A0F; } #sptp-7994 .sptp-member-profession .sptp-jop-title{ color:#9EA1B3; font-weight: 200; }<\/style><div class=\"sp-wp-team-pro-wrapper wp-team-pro-preloader\" > <div id=\"sptp-10617\" class=\"sp-team-pro sptp-section sptp-new_page pagination_normal sptp-even\" > <div class=\"sp-team-pro-page-loading-image\"><\/div> <div class=\"sptp-grid\"> <div class=\"sptp-row \"> <div class=\"sp-team-pro-item sptp-col-lg-1 sptp-col-md-1 sptp-col-sm-1 sptp-col-xs-1\" data-member=\"18933\"> <div class=\"sptp-member border-bg-around-member sptp-bottom-content sptp-square\"> <a class=\"sptp-member-avatar \" href=https:\/\/www.idisantiago.es\/gl\/team\/manuel-pombo-arias\/ target=_blank > <div class=\"sptp-member-avatar-img-area\" data-id=\"18933\"> <div class=\"sptp-member-avatar-img sptp-square sptp-icon-on-image \"> <div class=\"sptp-overflow-h\"> <div class=\"sptp-icon text-center\"> <i class=\"fa fa-plus\"><\/i> <\/div> <img loading=\"lazy\" decoding=\"async\" class=\"sptp_default_img \" src=\"https:\/\/www.idisantiago.es\/wp-content\/plugins\/wp-team-pro\/src\/Frontend\/img\/Placeholder-Image.png\" alt=\"Lidia Castro Feijoo\" width=\"600\" height=\"450\"> <\/div> <\/div> <\/div> <\/a> <div class=\"sptp-member-name \"> <h2 class=\"sptp-name\">Lidia Castro Feijoo<\/h2><\/div> <div class=\"sptp-read-more-button\"> <a class=\"sptp-member-read-more-button\" href=\"https:\/\/www.idisantiago.es\/gl\/team\/manuel-pombo-arias\/\" target=\"_blank\" > + INFO <\/a> <\/div> <\/div> <\/div> <\/div> <\/div> <\/div> <\/div> \n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00c1REA: ENDOCRINOLOX\u00cdAObxectivos Estudo da talla baixa: Bases moleculares e alternativas terap\u00e9uticas. Na \u00e1rea de crecemento \u00e9 interese fundamental para o noso grupo a investigaci\u00f3n do eixe hormonal GH- IGF1 e [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":10312,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"project_category":[505],"project_tag":[],"class_list":["post-16653","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-endocrinologia-gl"],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project\/16653","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/types\/project"}],"author":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/comments?post=16653"}],"version-history":[{"count":0,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project\/16653\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/media\/10312"}],"wp:attachment":[{"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/media?parent=16653"}],"wp:term":[{"taxonomy":"project_category","embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project_category?post=16653"},{"taxonomy":"project_tag","embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project_tag?post=16653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}