{"id":19240,"date":"2022-01-17T09:59:51","date_gmt":"2022-01-17T08:59:51","guid":{"rendered":"https:\/\/www.idisantiago.es\/grupo-de-investigacion\/c042-ictus-traslacional\/"},"modified":"2026-04-10T09:50:22","modified_gmt":"2026-04-10T07:50:22","slug":"c042-ictus-traslacional","status":"publish","type":"project","link":"https:\/\/www.idisantiago.es\/gl\/grupo-de-investigacion\/c042-ictus-traslacional\/","title":{"rendered":"C042 &#8211; Ictus Traslacional"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||||false|false&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; custom_padding=&#8221;0px||||false|false&#8221; locked=&#8221;on&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>\u00c1REA: <a href=\"https:\/\/www.idisantiago.es\/gl\/areas-de-investigacion\/a004-neurociencias\/\">NEUROCIENCIAS<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;2_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.idisantiago.es\/wp-content\/uploads\/2022\/02\/C042_B.jpg&#8221; title_text=&#8221;C042_B&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_toggle title=&#8221;Obxectivos e li\u00f1as de investigaci\u00f3n&#8221; admin_label=&#8221;Obxectivos e li\u00f1as de investigaci\u00f3n&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Obxectivos<\/h3>\n<p>Estudo e desenvolvemento de novas estratexias terap\u00e9uticas en patolox\u00edas neuronais, principalmente relacionadas coa isquemia cerebral. A nosa perspectiva \u00e9 intentar que todo o co\u00f1ecemento desenvolto no \u00e1mbito da investigaci\u00f3n te\u00f1a unha aplicaci\u00f3n traslacional e que repercuta no beneficio do paciente.<\/p>\n<h3>Li\u00f1as de investigaci\u00f3n<\/h3>\n<p>1. Neuroprotecci\u00f3n fronte \u00f3 dano excitot\u00f3xico na isquemia cerebral e ELA.<br \/>2. Estudo de mecanismos moleculares relacionados coa hipotermia na isquemia cerebral.<br \/>3. Desenvolvemento de nanoestruturas para a encapsulaci\u00f3n e liberaci\u00f3n controlada de f\u00e1rmacos na patolox\u00eda isqu\u00e9mica cerebral.<br \/>4. Uso da tecnolox\u00eda celular baseada na xeraci\u00f3n de c\u00e9lulas nai pluripotentes inducidas (iPSCs) en enfermidades monox\u00e9nicas causantes de ictus.<br \/>5. An\u00e1lise de biomarcadores asociados \u00f3 diagn\u00f3stico no ictus cerebral.<\/p>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Equipo investigador&#8221; admin_label=&#8221;Equipo investigador&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<table style=\"width: 100%; border-collapse: collapse; border-style: hidden;\" border=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\"><strong>L\u00edder<\/strong><br \/>Campos P\u00e9rez, Francisco<strong>Membros<\/strong><br \/>Arias Rivas, Susana<br \/>Bugallo Casal, Ana Isabel<br \/>Candamo Lourido, Mar\u00eda<br \/>Ca\u00f1izo Outeiri\u00f1o, Antonio<br \/>Del Pozo Fil\u00edu, Luc\u00eda<br \/>Dopico L\u00f3pez, Antonio<br \/>Garc\u00eda Sobrino, Tania<br \/>Laso Garc\u00eda, Fernando<br \/>L\u00f3pez Arias, Esteban<br \/>Otero Rial, Noelia<br \/>Palomar Alonso, Nuria<br \/>Pardo Fern\u00e1ndez, Julio<br \/>P\u00e9rez Gayol, Lara<br \/>P\u00e9rez L\u00e1zaro, Sonia<br \/>P\u00e9rez Mato, Mar\u00eda<br \/>Prego Dom\u00ednguez, Jes\u00fas<br \/>Rodr\u00edguez Y\u00e1\u00f1ez, Manuel<br \/>Santamar\u00eda Cadavid, Mar\u00eda<\/td>\n<td style=\"width: 50%;\">\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Proxectos&#8221; admin_label=&#8221;Proxectos (cambiar s\u00f3 codigo IDIS)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Publicaci\u00f3ns&#8221; admin_label=&#8221;Publicaci\u00f3ns&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li>Migliavacca M, Correa Paz C, P\u00e9rez-Mato M, Bielawski PB, Zhang I, Marie P, Hervella P, Rubio M, Maysinger D, Vivien D, Del Pino P, Pelaz B, Polo E, Campos F. <strong>Thrombolytic therapy based on lyophilized platelet-derived nanocarriers for ischemic stroke.<\/strong> <em>J Nanobiotechnology<\/em> 2024 <a href=\"https:\/\/doi.org\/10.1186\/s12951-023-02206-5\"><span style=\"color: #808000;\"><strong>DOI: 10.1186\/s12951-023-02206-5<\/strong><\/span><\/a><\/li>\n<li>Surpi A, Murgia M, L\u00f3pez-Amoedo S, Gonz\u00e1lez-G\u00f3mez MA, Pi\u00f1eiro Y, Rivas J, Perugini V, Santin M, Sobrino T, Greco P, Campos F and Dediu VA. <strong>Magnetic separation and concentration of A\u03b2 1-42 molecules dispersed at the threshold concentration for Alzheimer\u2019s disease diagnosis in clinically-relevant volumes of sample. <\/strong><em>J Nanobiotechnology. <\/em>2023 Sep 15;21(1):329. <span style=\"color: #808000;\"><strong><a style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.1186%2Fs12951-023-02095-8\">DOI: 10.1186\/s12951-023-02095-8<\/a><\/strong><\/span>.<\/li>\n<li>Alonso-Alonso ML, Sampedro-Viana A, Rodr\u00edguez-Y\u00e1\u00f1ez M, L\u00f3pez-Dequidt I, Pumar JM, Mosqueira AJ, Fern\u00e1ndez-Rodicio S, Bazarra-Barreiros M, Sobrino T, Campos F, Castillo J, Hervella P, Iglesias-Rey R.<strong> Influence of temperature chronobiology on stroke outcome<\/strong>. <em>Int J Mol Sci.<\/em> 2023 Feb 13;24(4):3746. <span style=\"color: #808000;\"><strong><span class=\"identifier doi\"><span class=\"id-label\">DOI:\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.3390\/ijms24043746\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.3390\/ijms24043746<\/a><\/span><\/strong><\/span><\/li>\n<li>Alonso-Alonso ML, Sampedro-Viana A, Fern\u00e1ndez-Rodicio S, Bazarra-Barreiros M, Ouro A, Sobrino T, Campos F, Castillo J, Hervella P, Iglesias-Rey R. <strong>Need for a paradigm shift in the treatment of cerebrovascular disease: the blood-brain barrier<\/strong>.\u00a0<em>Int J Mol Sci.<\/em> 2022 Aug 22;23(16):9486. <strong><span class=\"identifier doi\" style=\"color: #808000;\"><span class=\"id-label\">DOI:\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.3390\/ijms23169486\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.3390\/ijms23169486<\/a><\/span><\/strong><\/li>\n<li>Alonso-Alonso ML, Perez Mato M, Sampedro-Viana A, Correa-Paz C, Avila-Gomez P, Sobrino T, Campos F,\u00a0Castillo J, Iglesias-Rey R, Hervella P. <strong>Fibrin-Targeted Nanoparticles for Finding, Visualizing and Characterizing Blood Clots in Acute Ischemic Stroke.<\/strong> <em>Pharmaceutics<\/em><strong>. <\/strong>2022 Oct14; (10):2156. <span style=\"color: #808000;\"><strong><span class=\"identifier doi\"><span class=\"id-label\">DOI:\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.3390\/pharmaceutics14102156\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.3390\/pharmaceutics14102156<\/a><\/span><\/strong><\/span><\/li>\n<li>Mishra A, et al.<strong> Stroke genetics informs drug discovery and risk prediction across ancestries<\/strong>. <em>Nature<\/em>. 2022 Sep 30;1-15.\u00a0<span style=\"color: #808000;\"><strong><span class=\"identifier doi\"><span class=\"id-label\">DOI:\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.1038\/s41586-022-05165-3\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.1038\/s41586-022-05165-3<\/a><\/span><\/strong><\/span><\/li>\n<li>C\u00e1rcel-M\u00e1rquez J, et al. <strong>A Polygenic Risk Score Based on a Cardioembolic Stroke Multitrait Analysis Improves a Clinical Prediction Model for This Stroke Subtype<\/strong>. <em>Front Cardiovasc Med<\/em>. 2022 Jul 8; 9:940696. <span style=\"color: #808000;\"><strong><span class=\"identifier doi\"><span class=\"id-label\">DOI:\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.3389\/fcvm.2022.940696\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.3389\/fcvm.2022.940696<\/a><\/span><\/strong><\/span><\/li>\n<li>Alonso-Alonso ML, Sampedro-Viana A, Rodr\u00edguez-Y\u00e1\u00f1ez M, L\u00f3pez-Dequidt I, Pumar JM, J. Mosqueira A, Ouro A, \u00c1vila-G\u00f3mez P, Sobrino T, Campos F,\u00a0Castillo J, Hervella P, Iglesias-Rey R. <strong>Antihyperthermic Treatment in the Management of Malignant Infarction of the Middle Cerebral Artery<\/strong>. <em>Clin. Med<\/em>. 2022 May 19;11(10):2874.\u00a0<span style=\"color: #808000;\"><strong><span class=\"identifier doi\"><span class=\"id-label\">DOI:\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.3390\/jcm11102874\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.3390\/jcm11102874<\/a><\/span><\/strong><\/span><\/li>\n<\/ul>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Web do grupo&#8221; admin_label=&#8221;Web do grupo&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><a href=\"https:\/\/treatneurolab.com\/\">https:\/\/treatneurolab.com\/<\/a><\/p>\n<p>[\/et_pb_toggle][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Investigador\/a l\u00edder&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#10294c&#8221; custom_margin=&#8221;0px||||false|false&#8221; custom_padding=&#8221;6px||0px|6px|false|false&#8221; locked=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Investigador l\u00edder<\/h2>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;WP Team (cambiar s\u00f3 a ID pola do l\u00edder de equipo)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; locked=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<style id=\"team_pro_dynamic_css10821\">#sptp-10821 .sptp-main-carousel.swiper-container.center .sp-team-pro-item:not(.swiper-slide-active){opacity:.5;}#sptp-10821 .filters-button-group{justify-content:center;margin:0px 0px 23px 0px;}#sptp-10821 .filters-button-group 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class=\"sp-team-pro-item sptp-col-lg-1 sptp-col-md-1 sptp-col-sm-1 sptp-col-xs-1\" data-member=\"18912\"> <div class=\"sptp-member border-bg-around-member sptp-bottom-content sptp-square\"> <a class=\"sptp-member-avatar \" href=https:\/\/www.idisantiago.es\/gl\/team\/francisco-campos-perez\/ target=_blank > <div class=\"sptp-member-avatar-img-area\" data-id=\"18912\"> <div class=\"sptp-member-avatar-img sptp-square sptp-icon-on-image \"> <div class=\"sptp-overflow-h\"> <div class=\"sptp-icon text-center\"> <i class=\"fa fa-plus\"><\/i> <\/div> <img loading=\"lazy\" decoding=\"async\" class=\"sptp_default_img \" src=\"https:\/\/www.idisantiago.es\/wp-content\/uploads\/2022\/02\/Francisco-Campos-320x320.jpg\" alt=\"Francisco Campos P\u00e9rez\" width=\"320\" height=\"320\"> <\/div> <\/div> <\/div> <\/a> <div class=\"sptp-member-name \"> <h2 class=\"sptp-name\">Francisco Campos P\u00e9rez<\/h2><\/div> <div class=\"sptp-member-email\"> <i class=\"fa fa-envelope\"><\/i> <a href=\"#0\" class=\"\"> <span>francisco.campos.perez@sergas.es<\/span> <\/a> <\/div> <div class=\"sptp-member-website\"> <i class=\"fa fa-globe\"><\/i> <a href=\"http:\/\/orcid.org\/0000-0001-8665-1039\" class=\"\" target=\"_blank\"> <span>http:\/\/orcid.org\/0000-0001-8665-1039<\/span> <\/a> <\/div> <div class=\"sptp-read-more-button\"> <a class=\"sptp-member-read-more-button\" href=\"https:\/\/www.idisantiago.es\/gl\/team\/francisco-campos-perez\/\" target=\"_blank\" > + INFO <\/a> <\/div> <\/div> <\/div> <\/div> <\/div> <\/div> <\/div> \n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00c1REA: NEUROCIENCIASObxectivos Estudo e desenvolvemento de novas estratexias terap\u00e9uticas en patolox\u00edas neuronais, principalmente relacionadas coa isquemia cerebral. A nosa perspectiva \u00e9 intentar que todo o co\u00f1ecemento desenvolto no \u00e1mbito da [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":16399,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"project_category":[511],"project_tag":[],"class_list":["post-19240","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-neurociencias-gl"],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project\/19240","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/types\/project"}],"author":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/comments?post=19240"}],"version-history":[{"count":0,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project\/19240\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/media\/16399"}],"wp:attachment":[{"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/media?parent=19240"}],"wp:term":[{"taxonomy":"project_category","embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project_category?post=19240"},{"taxonomy":"project_tag","embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project_tag?post=19240"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}