{"id":19267,"date":"2022-01-14T11:37:48","date_gmt":"2022-01-14T10:37:48","guid":{"rendered":"https:\/\/www.idisantiago.es\/grupo-de-investigacion\/e043-fisica-medica-y-biomatematicas\/"},"modified":"2026-06-11T13:26:28","modified_gmt":"2026-06-11T11:26:28","slug":"e043-fisica-medica-y-biomatematicas","status":"publish","type":"project","link":"https:\/\/www.idisantiago.es\/gl\/grupo-de-investigacion\/e043-fisica-medica-y-biomatematicas\/","title":{"rendered":"E043 &#8211; F\u00edsica M\u00e9dica e Biomatem\u00e1ticas"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||||false|false&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; custom_padding=&#8221;0px||||false|false&#8221; locked=&#8221;off&#8221; collapsed=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>\u00c1REA: <a href=\"https:\/\/www.idisantiago.es\/gl\/areas-de-investigacion\/a001-oncoloxia\/\">ONCOLOX\u00cdA<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;2_3,1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.idisantiago.es\/wp-content\/uploads\/2021\/11\/grupo_investigacion.jpg&#8221; title_text=&#8221;Corporate portrait of office workers and employees&#8221; disabled_on=&#8221;on|on|on&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_toggle title=&#8221;Obxectivos e li\u00f1as de investigaci\u00f3n&#8221; admin_label=&#8221;Obxectivos e li\u00f1as de investigaci\u00f3n&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Obxectivos<\/h3>\n<p>O Grupo de F\u00edsica M\u00e9dica e Biomatem\u00e1ticas est\u00e1 interesado en m\u00faltiples aplicaci\u00f3ns da f\u00edsica e as matem\u00e1ticas en biomedicina, especialmente en oncolox\u00eda e radioterapia. O papel que xoga o modelado f\u00edsico\/matem\u00e1tico na biomedicina est\u00e1 aumentando d\u00eda a d\u00eda, particularmente motivado pola gran cantidade de datos cl\u00ednicos que est\u00e1n dispo\u00f1ibles na actualidade. Isto permite desenvolver ferramentas\/modelos de an\u00e1lises m\u00e1is fiables. Os modelos poden, por exemplo, axudar na interpretaci\u00f3n de datos experimentais ou desempe\u00f1ar un papel m\u00e1is ambicioso no dese\u00f1o de novas estratexias terap\u00e9uticas.<br \/>La principal motivaci\u00f3n de noso grupo \u00e9 contribu\u00edr \u00f3 desenvolvemento de novas estratexias terap\u00e9uticas individualizadas, mediante o emprego dun enfoque multidisciplinario que involucre a investigadores con perf\u00eds complementarios.<\/p>\n<h3>Li\u00f1as de investigaci\u00f3n<\/h3>\n<ul>\n<li>Modelos tumorais in silico e resposta a tratamento.<\/li>\n<li>Modelado da toxicidade en radioterapia.<\/li>\n<li>Efectos do dano indirecto en SBRT e radioinmunoterapia.<\/li>\n<li>Modelos farmacocin\u00e9ticos.<\/li>\n<li>Dosimetr\u00eda en radioterapia metab\u00f3lica.<\/li>\n<li>Detectores de radiaci\u00f3n en radioterapia FLASH.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Equipo investigador&#8221; admin_label=&#8221;Equipo investigador&#8221; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<table style=\"width: 100%; border-collapse: collapse; border-style: hidden;\" border=\"0\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\"><strong>L\u00edder<\/strong><br \/>Pardo Montero, Juan<\/p>\n<p><strong>Membros<\/strong><br \/>Gago Arias, Mar\u00eda Araceli<br \/>Gonz\u00e1lez Kolmel, Eva<br \/>L\u00f3pez Pouso, \u00d3scar<br \/>Otero Casal, Pedro<br \/>Rodr\u00edguez Caridad, David<\/p>\n<\/td>\n<td style=\"width: 50%;\">\u00a0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Proxectos&#8221; admin_label=&#8221;Proyectos (cambiar s\u00f3 codigo IDIS)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; locked=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Publicaci\u00f3ns&#8221; admin_label=&#8221;Publicaciones&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li>Rodr\u00edguez-Barbeito P, D\u00edz-Botana P, Gago-Arias A &#8230;, Pardo-Montero J.<strong> A model of indirect cell death caused by tumor vascular damage after high-dose radiotherapy.<\/strong>\u00a0<em>Cancer Research<\/em> 2019;79(23):6044-53.2. <a href=\"https:\/\/doi.org\/10.1158\/0008-5472.can-19-0181\"><span style=\"color: #808000;\"><strong><span class=\"metadata-label\">doi:<\/span>\u00a010.1158\/0008-5472.CAN-19-0181<\/strong><\/span><\/a><\/li>\n<li>Neira S, Brualla-G\u00f3nzalez L, Prieto-Pena J, G\u00f3mez F, Pardo-Montero J. <strong>A kinetic model of diode detector response to pulsed radiation beams<\/strong>. <em>Physics in Medicine &amp; Biology<\/em> 2020;64 (20):205007.<span style=\"color: #808000;\"><strong> doi<span class=\"identifier doi\"><span class=\"id-label\">: <\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.1088\/1361-6560\/ab4460\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.1088\/1361-6560\/ab4460<\/a><\/span><\/strong><\/span><\/li>\n<li>Neira S, Guiu-Souto J &#8230; Pardo-Montero J. <strong>Quantification of internal dosimetry in PET patients: individualized Monte Carlo vs generic phantom-based calculations.<\/strong> <em>Med Phys<\/em> 2020:47;4574-45884. <span style=\"color: #808000;\"><strong>doi:<span class=\"identifier doi\"><span class=\"id-label\">\u00a0<\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.1002\/mp.14344\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.1002\/mp.14344<\/a><\/span><\/strong><\/span><\/li>\n<li>Parga-Pazos M, L\u00f3pez Pouso \u00d3, Fenwick JD, Pardo-Montero J. <strong>A mathematical model of dynamics of cell populations in squamous epithelium after irradiation<\/strong>,<em> International Journal of Radiation Biology<\/em> 2020;96:1165-1172. <strong><span style=\"color: #808000;\">doi: <span class=\"identifier doi\"><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.1080\/09553002.2020.1787540\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.1080\/09553002.2020.1787540<\/a><\/span><\/span><\/strong><\/li>\n<li>Gago-Arias A, Neira, S, Pombar M, G\u00f3mez-Caama\u00f1o A, Pardo-Montero J.<strong> Evaluation of indirect damage and damage saturation effects in dose-response curves of hypofractionated radiotherapy of early-stage NSCLC and brain metastases<\/strong>. <em>Radiotherapy and Oncology<\/em> 2021;161:1-8.<span style=\"color: #808000;\"><strong> doi: <a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.1016\/j.radonc.2021.05.012\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.1016\/j.radonc.2021.05.012<\/a><\/strong><\/span><\/li>\n<li>Gago-Arias A, Neira S, Terragni F, Pardo-Montero J. <strong>A Mathematical Model of Thyroid Disease Response to Radiotherapy<\/strong>. <em>Mathematics<\/em> 2021;9(19);2365. <strong><span style=\"color: #808000;\"><a style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.3390\/math9192365\">doi: 10.3390\/math9192365<\/a><\/span><\/strong><\/li>\n<li>Neira S, Gago-Arias A, G\u00f3nzalez-Crespo I, Guiu-Souto J, Pardo-Montero J.<strong> Development of a Compartmental Pharmacokinetic Model for Molecular Radiotherapy with 131I-CLR1404<\/strong>. <em>Pharmaceutics<\/em> 2021;13:1497. <span style=\"color: #808000;\"><strong>doi:\u00a0<a style=\"color: #808000;\" href=\"https:\/\/dx.doi.org\/10.3390%2Fpharmaceutics13091497\" target=\"_blank\" rel=\"noopener noreferrer\">10.3390\/pharmaceutics13091497<\/a><\/strong><\/span><\/li>\n<li>Neira S, Guiu-Souto J, \u2026 Pardo-Montero J.<strong> Quantification of internal dosimetry in PET patients II: Individualized Monte Carlo\u2010based dosimetry for [18F] fluorocholine PET.<\/strong> <em>Medical Physics<\/em> 2021;48 (9):5448-5458. <span style=\"color: #808000;\"><strong>doi<span class=\"identifier doi\"><span class=\"id-label\">: <\/span><a class=\"id-link\" style=\"color: #808000;\" href=\"https:\/\/doi.org\/10.1002\/mp.15090\" target=\"_blank\" rel=\"noopener\" data-ga-category=\"full_text\" data-ga-action=\"DOI\">10.1002\/mp.15090<\/a><\/span><\/strong><\/span><\/li>\n<\/ul>\n<p>[\/et_pb_toggle][et_pb_toggle title=&#8221;Web do grupo&#8221; disabled_on=&#8221;on|on|on&#8221; admin_label=&#8221;Web del grupo&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; body_font=&#8221;|300|||||||&#8221; disabled=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>https:\/\/<\/p>\n<p>[\/et_pb_toggle][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text admin_label=&#8221;Investigador\/a l\u00edder&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#FFFFFF&#8221; header_text_color=&#8221;#FFFFFF&#8221; header_2_text_align=&#8221;left&#8221; header_2_text_color=&#8221;#FFFFFF&#8221; background_color=&#8221;#10294c&#8221; custom_margin=&#8221;0px||||false|false&#8221; custom_padding=&#8221;6px||0px|6px|false|false&#8221; locked=&#8221;on&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Investigador l\u00edder<\/h2>\n<p>[\/et_pb_text][et_pb_text admin_label=&#8221;WP Team (cambiar s\u00f3 a ID pola do l\u00edder de equipo)&#8221; _builder_version=&#8221;4.16&#8243; _module_preset=&#8221;default&#8221; locked=&#8221;on&#8221; 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.sptp-col-lg-1.sptp-member:nth-child(2n) .sptp-arrow, .sptp-mosaic .sptp-col-lg-2.sptp-member:nth-child(4n) .sptp-arrow, .sptp-mosaic .sptp-col-lg-2.sptp-member:nth-child(4n-1) .sptp-arrow, .sptp-mosaic .sptp-col-lg-3.sptp-member:nth-child(6n) .sptp-arrow, .sptp-mosaic .sptp-col-lg-3.sptp-member:nth-child(6n-1) .sptp-arrow, .sptp-mosaic .sptp-col-lg-3.sptp-member:nth-child(6n-2) .sptp-arrow, .sptp-mosaic .sptp-col-lg-4.sptp-member:nth-child(8n) .sptp-arrow, .sptp-mosaic .sptp-col-lg-4.sptp-member:nth-child(8n-1) .sptp-arrow, .sptp-mosaic .sptp-col-lg-4.sptp-member:nth-child(8n-2) .sptp-arrow, .sptp-mosaic .sptp-col-lg-4.sptp-member:nth-child(8n-3) .sptp-arrow { left: auto; right: -20px; border-left-width: 20px; border-right-width: 0; } }div, h2, h4,.sptp-member-name-title { font-family: 'Roboto'; } #sptp-7994 .sptp-member-name .sptp-member-name-title{ color:#8A7A0F; } #sptp-7994 .sptp-member-profession .sptp-jop-title{ color:#9EA1B3; font-weight: 200; }<\/style><div class=\"sp-wp-team-pro-wrapper wp-team-pro-preloader\" > <div id=\"sptp-10518\" class=\"sp-team-pro sptp-section sptp-new_page pagination_normal sptp-even\" > <div class=\"sp-team-pro-page-loading-image\"><\/div> <div class=\"sptp-grid\"> <div class=\"sptp-row \"> <div class=\"sp-team-pro-item sptp-col-lg-1 sptp-col-md-1 sptp-col-sm-1 sptp-col-xs-1\" data-member=\"18943\"> <div class=\"sptp-member border-bg-around-member sptp-bottom-content sptp-square\"> <a class=\"sptp-member-avatar \" href=https:\/\/www.idisantiago.es\/gl\/team\/juan-pardo-montero\/ target=_blank > <div class=\"sptp-member-avatar-img-area\" data-id=\"18943\"> <div class=\"sptp-member-avatar-img sptp-square sptp-icon-on-image \"> <div class=\"sptp-overflow-h\"> <div class=\"sptp-icon text-center\"> <i class=\"fa fa-plus\"><\/i> <\/div> <img loading=\"lazy\" decoding=\"async\" class=\"sptp_default_img \" src=\"https:\/\/www.idisantiago.es\/wp-content\/uploads\/2022\/02\/foto-320x320.jpeg\" alt=\"Juan Pardo Montero\" width=\"320\" height=\"320\"> <\/div> <\/div> <\/div> <\/a> <div class=\"sptp-member-name \"> <h2 class=\"sptp-name\">Juan Pardo Montero<\/h2><\/div> <div class=\"sptp-member-email\"> <i class=\"fa fa-envelope\"><\/i> <a href=\"#0\" class=\"\"> <span>juan.pardo.montero@sergas.es<\/span> <\/a> <\/div> <div class=\"sptp-member-phone\"> <i class=\"fa fa-phone\"><\/i> <a href=\"#0\" class=\"\" > <span>(+34) 981 955 604<\/span> <\/a> <\/div> <div class=\"sptp-member-website\"> <i class=\"fa fa-globe\"><\/i> <a href=\"https:\/\/orcid.org\/0000-0001-7990-3971\" class=\"\" target=\"_blank\"> <span>https:\/\/orcid.org\/0000-0001-7990-3971<\/span> <\/a> <\/div> <div class=\"sptp-read-more-button\"> <a class=\"sptp-member-read-more-button\" href=\"https:\/\/www.idisantiago.es\/gl\/team\/juan-pardo-montero\/\" target=\"_blank\" > + INFO <\/a> <\/div> <\/div> <\/div> <\/div> <\/div> <\/div> <\/div> \n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00c1REA: ONCOLOX\u00cdAObxectivos O Grupo de F\u00edsica M\u00e9dica e Biomatem\u00e1ticas est\u00e1 interesado en m\u00faltiples aplicaci\u00f3ns da f\u00edsica e as matem\u00e1ticas en biomedicina, especialmente en oncolox\u00eda e radioterapia. O papel que xoga [&hellip;]<\/p>\n","protected":false},"author":11,"featured_media":12107,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"project_category":[513],"project_tag":[],"class_list":["post-19267","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-oncologia-gl"],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project\/19267","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project"}],"about":[{"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/types\/project"}],"author":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/comments?post=19267"}],"version-history":[{"count":0,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project\/19267\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/media\/12107"}],"wp:attachment":[{"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/media?parent=19267"}],"wp:term":[{"taxonomy":"project_category","embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project_category?post=19267"},{"taxonomy":"project_tag","embeddable":true,"href":"https:\/\/www.idisantiago.es\/gl\/wp-json\/wp\/v2\/project_tag?post=19267"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}