{"id":34549,"date":"2024-06-10T11:19:23","date_gmt":"2024-06-10T09:19:23","guid":{"rendered":"https:\/\/www.idisantiago.es\/?post_type=project&p=34549"},"modified":"2025-06-10T11:58:41","modified_gmt":"2025-06-10T09:58:41","slug":"e063-neuroendocrine-regulation-of-metabolism-neuromet","status":"publish","type":"project","link":"https:\/\/www.idisantiago.es\/gl\/grupo-de-investigacion\/e063-neuroendocrine-regulation-of-metabolism-neuromet\/","title":{"rendered":"E063 – Neuroendocrine Regulation of Metabolism (NeuRoMet)"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.16″ _module_preset=”default” custom_padding=”0px||||false|false” da_disable_devices=”off|off|off” global_colors_info=”{}” da_is_popup=”off” da_exit_intent=”off” da_has_close=”on” da_alt_close=”off” da_dark_close=”off” da_not_modal=”on” da_is_singular=”off” da_with_loader=”off” da_has_shadow=”on”][et_pb_row _builder_version=”4.16″ _module_preset=”default” width=”100%” custom_padding=”0px||||false|false” locked=”on” collapsed=”on” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]\u00c1REA: ENDOCRINOLOG\u00cdA, NUTRICI\u00d3N Y METABOLISMO<\/a>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”2_3,1_3″ _builder_version=”4.16″ _module_preset=”default” width=”100%” global_colors_info=”{}”][et_pb_column type=”2_3″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_image title_text=”IMG-20230418-WA0000″ disabled_on=”on|on|on” _builder_version=”4.21.0″ _module_preset=”default” disabled=”on” global_colors_info=”{}”][\/et_pb_image][et_pb_toggle title=”Obxectivos e li\u00f1as de investigaci\u00f3n” disabled_on=”on|on|on” admin_label=”Objetivos y l\u00edneas de investigaci\u00f3n” _builder_version=”4.21.0″ _module_preset=”default” body_font=”|300|||||||” disabled=”on” global_colors_info=”{}”]<\/p>\n

Objetivos<\/h3>\n

 <\/p>\n

L\u00edneas de investigaci\u00f3n<\/h3>\n

L\u00edneas 2018-2023<\/strong><\/p>\n

    \n
  • Lipotoxicidad y ER stress hipotal\u00e1micos en la regulaci\u00f3n del balance energ\u00e9tico y su relevancia en el desarrollo de la diabetes y la obesidad.<\/li>\n
  • Mecanismos centrales de los estr\u00f3genos en la regulaci\u00f3n de la termog\u00e9nesis BAT y la ingesta.<\/li>\n
  • Fisiolog\u00eda de la termog\u00e9nesis neonatal humana.<\/li>\n<\/ul>\n

    L\u00edneas 2023-2028<\/strong><\/p>\n

      \n
    • Receptores nucleares hipotal\u00e1micos en la regulaci\u00f3n del equilibrio energ\u00e9tico y la obesidad.<\/li>\n
    • El papel neuroendocrino de los astrocitos en el hipot\u00e1lamo.<\/li>\n
    • Efectos de los estr\u00f3genos sobre los neurocircuitos implicados en el control de la fisiolog\u00eda.<\/li>\n<\/ul>\n

       <\/p>\n

      [\/et_pb_toggle][et_pb_toggle title=”Equipo investigador” admin_label=”Equipo investigador” _builder_version=”4.21.0″ _module_preset=”default” body_font=”|300|||||||” hover_enabled=”0″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n\n\n\n
      L\u00edder<\/strong>
      Gonz\u00e1lez Garc\u00eda, Ismael<\/p>\n

      Membros<\/strong>
      Fern\u00e1ndez Malvido, Nicol\u00e1s
      Jose Vattathara, Jane
      Otero Rey, Alicia<\/p>\n<\/td>\n

      		\u00a0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

      [\/et_pb_toggle][et_pb_toggle title=”Proxectos” disabled_on=”on|on|on” admin_label=”Proyectos (cambiar s\u00f3 codigo IDIS)” _builder_version=”4.21.0″ _module_preset=”default” body_font=”|300|||||||” disabled=”on” locked=”off” global_colors_info=”{}”]<\/p>\n\n

      [\/et_pb_toggle][et_pb_toggle title=”Publicaci\u00f3ns” disabled_on=”off|off|off” admin_label=”Publicaciones” _builder_version=”4.21.0″ _module_preset=”default” body_font=”|300|||||||” global_colors_info=”{}”]<\/p>\n

        \n
      • Dragano NRV, Milbank E, Haddad-T\u00f3volli R, Garrido-Gil P, N\u00f3voa E, Fondevilla MF, Capelli V, Zanesco AM, Solon C, Morari J, Pires L, Estevez-Salguero \u00c1, Beiroa D, Gonz\u00e1lez-Garc\u00eda I, Barca-Mayo O, Di\u00e9guez C, Nogueiras R, Labandeira- Garc\u00eda JL, Ulven ER, Ulven T, Claret M, Velloso LA, Lopez M. Hypothalamic free fatty acid receptor-1 regulates whole-body energy balance.<\/strong> PMID: 38036170. Mol Metab. 2023 Nov 29:101840.<\/li>\n
      • Gruber T, Lechner F, Murat C, Contreras RE, Sanchez-Quant E, Miok V, Makris K, Le Thuc O, Gonz\u00e1lez-Garc\u00eda I, Garc\u00eda-Clave E, Althammer F, Krabichler Q, DeCamp LM, Jones RG, Lutter D, Williams RH, Pfluger PT, M\u00fcller TD, Woods SC, Pospisilik JA, Martinez-Jimenez CP, Tsch\u00f6p MH, Grinevich V, Garc\u00eda-C\u00e1ceres C. High-calorie diets uncouple hypothalamic oxytocin neurons from a gut-to-brain satiation pathway via \u03ba-opioid signaling.<\/strong> PMID: 37864798 Cell Rep. 2023 Oct 31;42(10):113305.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, Garc\u00eda-C\u00e1ceres C. Astrocytic GABA in LHA is an obesity ‘thermostat’.<\/strong> PMID: 37653042. Nat Metab. 2023 Sep;5(9):1454-1455.<\/li>\n
      • Gonz\u00e1lez Garc\u00eda I, L\u00f3pez M. Fezolinetant for menopausal hot flashes and night sweats.<\/strong> PMID: 37423792. Trends Pharmacol Sci. 2023 Sep;44(9):635-636.<\/li>\n
      • Zagmutt S, Mera P, Gonz\u00e1lez-Garc\u00eda I, Ibeas K, Romero MDM, Obri A, Martin B, Esteve-Codina A, Soler-V\u00e1zquez MC, Bastias-P\u00e9rez M, Ca\u00f1es L, Aug\u00e9 E, Pelegri C, Vilaplana J, Ariza X, Garc\u00eda J, Martinez-Gonz\u00e1lez J, Casals N, L\u00f3pez M, Palmiter R, Sanz E, Quintana A, Herrero L, Serra D. CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst.<\/strong> PMID: 36966335. Biol Sex Differ. 2023 Mar 25;14(1):14.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, Garc\u00eda-Clav\u00e9 E, Cebrian-Serrano A, Le Thuc O, Contreras RE, Xu Y, Gruber T, Schriever SC, Legutko B, Lintelmann J, Adamski J, Wurst W, M\u00fcller TD, Woods SC, Pfluger PT, Tsch\u00f6p MH, Fisette A, Garc\u00eda-C\u00e1ceres C. Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1.<\/strong> PMID: 36889283.\u00a0 Cell Metab. 2023 Mar 7;35(3):438-455.e7.<\/li>\n
      • Lutomska LM, Miok V, Krahmer N, Gonz\u00e1lez Garc\u00eda I, Gruber T, Le Thuc O, Murat CD, Legutko B, Sterr M, Saher G, Lickert H, M\u00fcller TD, Ussar S, Tsch\u00f6p MH, Lutter D, Garc\u00eda-C\u00e1ceres C. Diet triggers specific responses of hypothalamic astrocytes in time and region dependent manner.<\/strong> PMID: 35802021. Glia. 2022 Nov;70(11):2062-2078.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, Urisarri A, Nogueiras R, Di\u00e9guez C, Couce ML, L\u00f3pez M. An updated view on human neonatal thermogenesis.<\/strong> PMID: 35165402. Nat Rev Endocrinol. 2022 May;18(5):263-264.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, Freire-Agulleiro \u00d3, Nakaya N, Ortega FJ, Garrido-Gil P, Li\u00f1ares-Pose L, Fern\u00f8 J, Labandeira-Garcia JL, Di\u00e9guez C, Sultana A, Tomarev SI, Fern\u00e1ndez-Real JM, L\u00f3pez M. Olfactomedin 2 deficiency protects against diet-induced obesity.<\/strong> PMID: 35026233.\u00a0 Metabolism. 2022 Apr;129:155122.<\/li>\n
      • Tarquis-Medina M, Scheibner K, Gonz\u00e1lez-Garc\u00eda I, Bastidas-Ponce A, Sterr M, Jaki J, Schirge S, Garc\u00eda-C\u00e1ceres C, Lickert H, Bakhti M. Synaptotagmin-13 Is a Neuroendocrine Marker in Brain, Intestine and Pancreas.<\/strong> PMID: 34830411.\u00a0 Int J Mol Sci. 2021 Nov 20;22(22):12526.<\/li>\n
      • Milbank E, Dragano NRV, Gonz\u00e1lez-Garc\u00eda I, Garcia MR, Rivas-Limeres V, Perdomo L, Hilairet G, Ruiz-Pino F, Mallegol P, Morgan DA, Iglesias-Rey R, Contreras C, Vergori L, Cu\u00f1arro J, Porteiro B, Gavald\u00e0-Navarro A, Oelkrug R, Vidal A, Roa J, Sobrino T, Villarroya F, Di\u00e9guez C, Nogueiras R, Garc\u00eda-C\u00e1ceres C, Tena-Sempere M, Mittag J, Carmen Mart\u00ednez M, Rahmouni K, Andriantsitohaina R, L\u00f3pez M. Small extracellular vesicle-mediated targeting of hypothalamic AMPK\u03b11 corrects obesity through BAT activation.<\/strong> PMID: 34675439.\u00a0 Nat Metab. 2021 Oct;3(10):1415-1431.<\/li>\n
      • Urisarri A, Gonz\u00e1lez-Garc\u00eda I, Est\u00e9vez-Salguero \u00c1, Pata MP, Milbank E, L\u00f3pez N, Mandi\u00e1 N, Grijota-Martinez C, Salgado CA, Nogueiras R, Di\u00e9guez C, Villarroya F, Fern\u00e1ndez-Real JM, Couce ML, L\u00f3pez M. BMP8 and activated brown adipose tissue in human newborns.<\/strong> PMID: 34489410.\u00a0 Nat Commun. 2021 Sep 6;12(1):5274.<\/li>\n
      • Meneyrol K, Est\u00e9vez-Salguero \u00c1, Gonz\u00e1lez-Garc\u00eda I, Guitton J, Taouis M, Benomar Y, Magnan C, L\u00f3pez M, Le Stunff H. Ovarian insufficiency impairs glucose-stimulated insulin secretion through activation of hypothalamic de novo ceramide synthesis.<\/strong> PMID: 34371064.\u00a0 Metabolism. 2021 Oct;123:154846.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, Garc\u00eda-C\u00e1ceres C. Hypothalamic Astrocytes as a Specialized and Responsive Cell Population in Obesity.<\/strong> PMID: 34201099.\u00a0 Int J Mol Sci. 2021 Jun 8;22(12):6176.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, Gruber T, Garc\u00eda-C\u00e1ceres C. Insulin action on astrocytes: From energy homeostasis to behaviour.<\/strong> PMID: 33724579.\u00a0 J Neuroendocrinol. 2021 Apr;33(4):e12953.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, Le Thuc O, Jastroch M, Garc\u00eda-C\u00e1ceres C. Divide et impera: How mitochondrial fission in astrocytes rules obesity.<\/strong> PMID: 33400974. Mol Metab. 2021 Mar;45:101159.<\/li>\n
      • Badenes M, Amin A, Gonz\u00e1lez-Garc\u00eda I, F\u00e9lix I, Burbridge E, Cavadas M, Ortega FJ, de Carvalho \u00c9, Fa\u00edsca P, Carobbio S, Seixas E, Pedroso D, Neves-Costa A, Moita LF, Fern\u00e1ndez-Real JM, Vidal-Puig A, Domingos A, L\u00f3pez M, Adrain C. Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis.<\/strong> PMID: 31918923. Mol Metab. 2020 Jan;31:67-84.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, Milbank E, Martinez-Ordo\u00f1ez A, Di\u00e9guez C, L\u00f3pez M, Contreras C. HYPOTHesizing about central comBAT against obesity.<\/strong> PMID: 31845114.\u00a0 J Physiol Biochem. 2020 May;76(2):193-211.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, Milbank E, Di\u00e9guez C, L\u00f3pez M, Contreras C. Glucagon, GLP-1 and Thermogenesis.<\/strong> PMID: 31337027.\u00a0 Int J Mol Sci. 2019 Jul 13;20(14):3445.<\/li>\n
      • Blankenhaus B, Braza F, Martins R, Bastos-Amador P, Gonz\u00e1lez-Garc\u00eda I, Carlos AR, Mahu I, Faisca P, Nunes JM, Ventura P, Hoerr V, Weis S, Guerra J, Cardoso S, Domingos A, L\u00f3pez M, Soares MP. Ferritin regulates organismal energy balance and thermogenesis.<\/strong> PMID: 30954544.\u00a0 Mol Metab. 2019 Jun;24:64-79.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, Contreras C, Est\u00e9vez-Salguero \u00c1, Ru\u00edz-Pino F, Colsh B, Pensado I, Li\u00f1ares-Pose L, Rial-Pensado E, Mart\u00ednez de Morentin PB, Fern\u00f8 J, Di\u00e9guez C, Nogueiras R, Le Stunff H, Magnan C, Tena-Sempere M, L\u00f3pez M. Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress.<\/strong> PMID: 30304681. Cell Rep. 2018 Oct 9;25(2):413-423.e5.<\/li>\n
      • Li\u00f1ares-Pose L, Rial-Pensado E, Est\u00e9vez-Salguero \u00c1, Milbank E, Gonz\u00e1lez- Garc\u00eda I, Rodr\u00edguez C, Seoane-Collazo P, Martinez-S\u00e1nchez N, Nogueiras R, Prieto D, Di\u00e9guez C, Contreras C, L\u00f3pez M. Genetic Targeting of GRP78 in the VMH Improves Obesity Independently of Food Intake.<\/strong> PMID: 30018241.\u00a0 Genes (Basel). 2018 Jul 17;9(7):357.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, Mart\u00ednez de Morentin PB, Est\u00e9vez-Salguero \u00c1, Contreras C, Romero-Pic\u00f3 A, Fern\u00f8 J, Nogueiras R, Di\u00e9guez C, Tena-Sempere M, Tovar S, L\u00f3pez M. mTOR signaling in the arcuate nucleus of the hypothalamus mediates the anorectic action of estradiol.<\/strong> PMID: 29914932.\u00a0 J Endocrinol. 2018 Sep;238(3):177-186.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, Tena-Sempere M, L\u00f3pez M. Estradiol Regulation of Brown Adipose Tissue Thermogenesis.<\/strong> PMID: 29224101. Adv Exp Med Biol. 2017;1043:315 335.<\/li>\n
      • Skrede S, Gonz\u00e1lez-Garc\u00eda I, Martins L, Berge RK, Nogueiras R, Tena-Sempere M, Mellgren G, Steen VM, L\u00f3pez M, Fern\u00f8. Lack of Ovarian Secretions Reverts the Anabolic Action of Olanzapine in Female Rats.<\/strong> PMID: 29020342.\u00a0 J. Int J Neuropsychopharmacol. 2017 Dec 1;20(12):1005-1012.<\/li>\n
      • Gonz\u00e1lez Garc\u00eda I, Fern\u00f8 J, L\u00f3pez M. Central Oxytocin and Energy Balance: More Than Feelings.<\/strong> PMID: 28911180. Endocrinology. 2017 Sep 1;158(9):2713-2715.<\/li>\n
      • Mart\u00ednez-S\u00e1nchez N, Seoane-Collazo P, Contreras C, Varela L, Villarroya J, Rial-Pensado E, Buqu\u00e9 X, Aurrekoetxea I, Delgado TC, V\u00e1zquez-Mart\u00ednez R, Gonz\u00e1lez-Garc\u00eda I, Roa J, Whittle AJ, Gomez-Santos B, Velagapudi V, Tung YCL, Morgan DA, Voshol PJ, Mart\u00ednez de Morentin PB, L\u00f3pez-Gonz\u00e1lez T, Li\u00f1ares-Pose L, Gonzalez F, Chatterjee K, Sobrino T, Medina-G\u00f3mez G, Davis RJ, Casals N, Ore\u0161i\u010d M, Coll AP, Vidal-Puig A, Mittag J, Tena-Sempere M, Malag\u00f3n MM, Di\u00e9guez C, Mart\u00ednez-Chantar ML, Aspichueta P, Rahmouni K, Nogueiras R, Sabio G, Villarroya F, L\u00f3pez M. Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance.<\/strong> PMID: 28683288.Cell Metab. 2017 Jul 5;26(1):212-229.e12.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, L\u00f3pez M. UCP1 and T3: A key “(un)couple” in energy balance.<\/strong> PMID: 28349091. Temperature (Austin). 2016 Aug 5;4(1):18-20.<\/li>\n
      • Gonz\u00e1lez-Garc\u00eda I, Fern\u00f8 J, Di\u00e9guez C, Nogueiras R, L\u00f3pez M. Hypothalamic Lipids: Key Regulators of Whole Body Energy Balance.<\/strong> PMID: 27728904. Neuroendocrinology. 2017;104(4):398-411.<\/li>\n
      • Contreras C, Gonz\u00e1lez-Garc\u00eda I, Seoane Collazo P, Mart\u00ednez-S\u00e1nchez N, Li\u00f1ares-Pose L, Rial-Pensado E, Fern\u00f8 J, Tena-Sempere M, Casals N, Di\u00e9guez C, Nogueiras R, L\u00f3pez M. Reduction of Hypothalamic Endoplasmic Reticulum Stress Activates Browning of White Fat and Ameliorates Obesity.<\/strong> PMID: 27634226. Diabetes. 2017 Jan;66(1):87-99.<\/li>\n
      • Martins L, Seoane-Collazo P, Contreras C, Gonz\u00e1lez-Garc\u00eda I, Mart\u00ednez- S\u00e1nchez N, Gonz\u00e1lez F, Zalvide J, Gallego R, Di\u00e9guez C, Nogueiras R, Tena- Sempere M, L\u00f3pez M. A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance.<\/strong> PMID: 27524625. Cell Rep. 2016 Aug 23;16(8):2231-2242.<\/li>\n
      • Ortega-Molina A, Lopez-Guadamillas E, Mattison JA, Mitchell SJ, Mu\u00f1oz-Martin M, Iglesias G, Gutierrez VM, Vaughan KL, Szarowicz MD, Gonz\u00e1lez-Garc\u00eda I, L\u00f3pez M, Cebri\u00e1n D, Martinez S, Pastor J, de Cabo R, Serrano M. Pharmacological inhibition of PI3K reduces adiposity and metabolic syndrome in obese mice and rhesus monkeys.<\/strong> PMID: 25817535. Cell Metab. 2015 Apr 7;21(4):558-70.<\/li>\n
      • Mart\u00ednez de Morentin PB, Lage R, Gonz\u00e1lez-Garc\u00eda I, Ru\u00edz-Pino F, Martins L, Fern\u00e1ndez-Mallo D, Gallego R, Fern\u00f8 J, Se\u00f1ar\u00eds R, Saha AK, Tovar S, Di\u00e9guez C, Nogueiras R, Tena-Sempere M, L\u00f3pez M. Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-CoA and the thermogenic effect of hypothalamic AMPK inhibition in female rats.<\/strong> PMID: 25535827. Endocrinology. 2015 Mar;156(3):947-60.<\/li>\n
      • Fern\u00f8 J, Ersland KM, Duus IH, Gonz\u00e1lez-Garc\u00eda I, Fossan KO, Berge RK, Steen VM, Skrede S. Olanzapine depot exposure in male rats: Dose-dependent lipogenic effects without concomitant weight gain.<\/strong> PMID: 25823694. Eur Neuropsychopharmacol. 2015 Jun;25(6):923 32.<\/li>\n
      • Contreras C, Gonz\u00e1lez-Garc\u00eda I, Mart\u00ednez-S\u00e1nchez N, Seoane-Collazo P, Jacas J, Morgan DA, Serra D, Gallego R, Gonzalez F, Casals N, Nogueiras R, Rahmouni K, Di\u00e9guez C, L\u00f3pez M. Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance.<\/strong> PMID: 25284795. Cell Rep. 2014 Oct 9;9(1):366-377.<\/li>\n
      • Mart\u00ednez de Morentin PB, Gonz\u00e1lez-Garc\u00eda I, Martins L, Lage R, Fern\u00e1ndez- Mallo D, Mart\u00ednez-S\u00e1nchez N, Ru\u00edz-Pino F, Liu J, Morgan DA, Pinilla L, Gallego R, Saha AK, Kalsbeek A, Fliers E, Bisschop PH, Di\u00e9guez C, Nogueiras R, Rahmouni K, Tena-Sempere M, L\u00f3pez M. Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK.<\/strong> PMID: 24856932. Cell Metab. 2014 Jul 1;20(1):41-53.<\/li>\n<\/ul>\n

        [\/et_pb_toggle][et_pb_toggle title=”Web do grupo” disabled_on=”on|on|on” admin_label=”Web del grupo” _builder_version=”4.16″ _module_preset=”default” body_font=”|300|||||||” disabled=”on” global_colors_info=”{}”]https:\/\/[\/et_pb_toggle][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text admin_label=”Investigador\/a l\u00edder” _builder_version=”4.21.0″ _module_preset=”default” text_text_color=”#FFFFFF” header_text_color=”#FFFFFF” header_2_text_align=”left” header_2_text_color=”#FFFFFF” background_color=”#10294c” custom_margin=”0px||||false|false” custom_padding=”6px||0px|6px|false|false” locked=”off” global_colors_info=”{}”]<\/p>\n

        Investigadora l\u00edder<\/h2>\n

        [\/et_pb_text][et_pb_text admin_label=”WP Team (cambiar s\u00f3 a ID pola do l\u00edder de equipo)” _builder_version=”4.21.0″ _module_preset=”default” locked=”off” global_colors_info=”{}”]<\/p>\n

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        \n\t\t\t\t\t<\/i>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\"Ismael\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/a>\n\t
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        \n\t\t\t\t\tIsmael Gonz\u00e1lez Garc\u00eda\t\t\t\t<\/h2>\n\t<\/div>\n
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