Objectives and lines of research
Objectives
- Validation and Reproducibility of the Ambulatory Blood Pressure Monitoring Technique (ABPM) and Actigraphy. ABPM of 24 hours versus 48 hours
- Interrelation between Circadian Variation of Blood Pressure and Vascular Risk. Epidemiological, pathophysiological and clinical aspects.
- Network development for computerized management of clinical and medical research projects in the field of ABPM and Chronotherapy
Chronoepidemiology, Chronopharmacology and Antihypertensive Chronotherapy - Clinical Inertia in Vascular Medicine, focused on 3 aspects: Blood Pressure Measurement, Cardiovascular Risk Stratification and Therapeutic Attitude
- Development of a computer system (software) to measure the caliber of retinal vessels. Applications in the evaluation of cardiovascular risk in hypertensive patients
- Clinical Trials in Arterial Hypertension, Diabetes Mellitus, Dyslipidemias, Heart Failure and Cardiovascular Morbidity and Mortality
- Pathogenesis of the non-dipper circadian profile: molecular bases (Clock genes)
- Natriuresis, sodium metabolism and circadian variation in blood pressure
- Chronobiology and Chronotherapy in Heart Failure due to systolic and diastolic dysfunction
- Orthostatic hypotension, organ damage and circadian variability of blood pressure
- Central aortic arterial pressure and pulse pressure as markers of vascular risk. SphygmoCor System
masked hypertension - Blood pressure and cardiovascular risk in patients with HIV infection
- Postprandial glycemia and circadian variation of blood pressure in diabetic patients
- ABPM and Obstructive Sleep Apnea Syndrome
- Retinal microcirculation, arterial hypertension and antihypertensive treatment
Research team
Leader
Pose Reino, Antonio