C003 – Hypertension

Objectives and lines of research


  • Validation and Reproducibility of the Ambulatory Blood Pressure Monitoring Technique (ABPM) and Actigraphy. ABPM of 24 hours versus 48 hours
  • Interrelation between Circadian Variation of Blood Pressure and Vascular Risk. Epidemiological, pathophysiological and clinical aspects.
  • Network development for computerized management of clinical and medical research projects in the field of ABPM and Chronotherapy
    Chronoepidemiology, Chronopharmacology and Antihypertensive Chronotherapy
  • Clinical Inertia in Vascular Medicine, focused on 3 aspects: Blood Pressure Measurement, Cardiovascular Risk Stratification and Therapeutic Attitude
  • Development of a computer system (software) to measure the caliber of retinal vessels. Applications in the evaluation of cardiovascular risk in hypertensive patients
  • Clinical Trials in Arterial Hypertension, Diabetes Mellitus, Dyslipidemias, Heart Failure and Cardiovascular Morbidity and Mortality
  • Pathogenesis of the non-dipper circadian profile: molecular bases (Clock genes)
  • Natriuresis, sodium metabolism and circadian variation in blood pressure
  • Chronobiology and Chronotherapy in Heart Failure due to systolic and diastolic dysfunction
  • Orthostatic hypotension, organ damage and circadian variability of blood pressure
  • Central aortic arterial pressure and pulse pressure as markers of vascular risk. SphygmoCor System
    masked hypertension
  • Blood pressure and cardiovascular risk in patients with HIV infection
  • Postprandial glycemia and circadian variation of blood pressure in diabetic patients
  • ABPM and Obstructive Sleep Apnea Syndrome
  • Retinal microcirculation, arterial hypertension and antihypertensive treatment
Research team

Pose Reino, Antonio


Research staff (established or associate)
Calvo Gómez, Carlos
Hermida Ameijeiras, Álvaro
López Paz, José Enrique


Postdoctoral staff
Calvo González, Gaila
Mateos Álvarez, Raimundo
Pena Seijo, Marta
Riveiro Cruz, Manuel Alberto

Lead researcher