C006 – Molecular Endocrinology

Objectives and lines of research


Our research group addresses obesity as a general topic, with the aim of determining the mechanisms that originate it and perpetuate it over time, associated alterations such as diabetes and cancer, as well as possible future therapies. For this, different methodological approaches are carried out, such as: population monitoring studies, translational, molecular and cellular endocrinology.
Adipose tissue, as a key tissue where obesity originates, focuses many of the group’s lines of work, fundamentally on understanding the processes that make it a pathological tissue and why it has repercussions at a systemic level, which would make it possible to find new therapeutic approaches.
On the other hand, new lines of work have been opened regarding the recently discovered hormone: irisin, which could open a new path in understanding obesity.
Among our lines of work is: Biology of adipose tissue. Interactions between different anatomical regions, obesity and cancer, leptin and anorexia, immunization against obesogenic agents, nanotechnology applied to obesity and regulation of irisin expression and secretion.


Research team
Casanueva Freijo, Felipe


Personal Investigador (establecido o asociado)
Cantón Blanco, Ana
Martínez Olmos, Miguel Ángel

Andújar Plata, Paula
Martís Sueiro, Aurelio Manuel
Peinó García, Roberto

Castro Pais, Ana
Duyos Mato, Davia


Personal técnico de apoyo
Iglesias Moares, Jesús
Rendo Caneda, Maribel

Personal colaborador externo
Couselo Carreira, Marcos

Lead researcher

Felipe Casanueva Freijo

Felipe Casanueva Freijo