ÁREA: ONCOLOGÍA
Objectives and lines of research
Objectives
The Medical Oncology Service seeks to integrate care, research and teaching in the day-to-day work of all its members and in all its actions, present and future, with a collaborative vocation with other groups of IDIS, Sergas, the University and national and international with the ultimate mission of knowing and curing cancer. In research, clinical and translational research stands out. Currently we have 70 open clinical trials from phase I to phase IV, promoted by Pharmaceutical Companies, National and International Cooperative Groups and non-commercial research, in most tumor pathologies.
Lines of research
Translational research has as its main objective the metastasis process that aims to fully integrate research work into healthcare, and the ambitious commitment that research results feed the Clinical Trials Program and vice versa. The lines are:
- Liquid biopsy with the characterization and clinical value of Circulating Tumor Cells (CTC) and other blood products
- Invasion and metastasis: both the characterization of these mechanisms and their relationship with the biology of CTCs and the epithelial-mesenchymal transition are focused.
- Epigenetics (mainly methylation) in brain and pancreatic tumors
- New screening and modeling strategies in oncology: in close collaboration with the IDIS group led by Laura Sánchez, we are developing and applying the zebrafish animal model in oncology, both as a model for studying processes related to metastasis, and as a screening and application model
- Nanotechnology applied in oncology: in 2013 we created the nano-oncology laboratory, where we integrate nanotechnology for the development of new therapeutic strategies and diagnostic agents (nanotheranostics). There is also close collaboration with the IDIS NANOBIOFAR group led by María José Alonso
Research team
Leader
López López, Rafael
