E027 – Escherichia coli

Objectives and lines of research


  • Study of the pathogenesis, epidemiology and microbiological diagnosis of E. coli that cause infections in humans and animals. STEC/VTEC, ETEC, EPEC, EIEC, EAggEC, AEEC, AIEC, ExPEC
  • Determination of pathogenesis mechanisms and development of diagnostic techniques and molecular typing of verotoxigenic E. coli (VTEC/STEC) O104:H4, O157:H7, O26:H11, O103:H2, O111:H8, O121:H19, O145 :H- and other serotypes. Detection in clinical samples and food.
  • Development of analytical methods for the detection of STEC/VTEC and other categories of diarrheagenic E. coli in clinical samples and food (meat, dairy and vegetable products). Detection of STEC/VTEC O104:H4, O157:H7 and other serotypes by conventional and real-time PCR.
  • Determination of serotypes, virulence genes, and molecular typing of extraintestinal pathogenic E. coli (ExPEC) that cause urinary tract infections, sepsis, and meningitis in humans.
  • Establishment of the serotypes, virulence genes and molecular typing of E. coli producers of extended-spectrum beta-lactamases (ESBLs).
  • Characterization of the emerging intercontinental clone O25:H4-ST131 producer of CTX-M-15 and detection and identification of new emerging clones.
  • Development of vaccines against E. coli that cause infections in humans and animals.
Research team

Blanco Álvarez, Jorge

Researchers (established or associate)
Blanco Álvarez, Jesús Eulogio
Blanco Álvarez, Miguel
Mora Gutiérrez, Azucena


Postdoctoral staff
Coira Nieto, María Amparo
Flament Simón, Saskia Camille

García Menéndez, Vanesa
García Meniño, Isidro
Mayer Mayer, Celia

Predoctoral staff
Lestón Cambeiro, Luz

Lead researcher

Jorge Blanco Álvarez

Jorge Blanco Álvarez