Epigenomics
COMMON SUPPORT PLATFORMS
Equipment
- NextSeq500 (Illumina) equipment for massive sequencing (NGS)
- HiScan Microarray System (Illumina)
- PyroMark Q24 Pyrosequencer (Qiagen)
- StepOne Real-Time PCR Kit (Applied Biosystems)
As a complement to our equipment, we have other equipment available at our institution (IDIS), as well as access to the QX200 digital PCR equipment (Bio-Rad) from the IDIS Liquid Biopsy Analysis Unit.
Description
Epigenomics contributes to solving multiple biological processes related to the development of diseases and is very useful in the field of personalized medicine. The Epigenomics Unit, created in collaboration between the Endocrinology and Nutrition area and the Oncology area of IDIS and in consortium between FIDIS and the CIBER Physiopathology of Obesity and Nutrition (CIBERobn), aims to provide help and support to research groups and industry at a national and international level in carrying out epigenomic studies, at the level of specific genes or the epigenome.
Technology applications
The epigenetic studies carried out in the Epigenomics Unit will add value to any preclinical or clinical project that aims to study the molecular mechanisms involved in the development of different types of diseases. These studies can be both small-scale, to study epigenetic marks in individual genes or gene panels, and large-scale, performing a broader analysis of the epigenome. These analyzes carried out in the Epigenomics Unit will help to identify or evaluate epigenetic marks with clinical utility both in cell samples and frozen tissues or in paraffin, as well as in liquid biopsies of different biological fluids. Thus, the results obtained will be useful in the field of pharmacoepigenome, nutriepigenome and personalised medicine.
Services
Our Epigenomics Unit offers support and help in different phases of the epigenomic study:
- Advice and help in the design of the study
- Preparation and processing of biological samples
- Realization of different types of epigenetic and/or epigenomic methodologies
- Analysis, interpretation and delivery of results
Contact
