E034 – FarmaCHUSLab

Objectives and lines of research


In the field of clinical and translational research, the interests of our research group, made up mainly of members of the Pharmacy Service of the Santiago de Compostela Health Area with research and care training, are oriented towards a series of fundamental aspects:
1.Personalization of pharmacological treatments: contribute to revealing the bases of variability in the response to drugs and optimize the results of pharmacological therapies.
2. Development and galenic characterization of medicines

Lines of research

  • Development of drugs and personalized formulations (Galeno 4.0): Currently there is a significant number of patients with no treatment available, who do not have treatments adapted to their disease and/or specific condition. At this point, the galenic sections of the Pharmacy Service are in charge of responding. The “Galeno 4.0” line has meant a reinvention in the development and optimization of personalized formulations adapted to the patient, and the group is currently a national benchmark in this field. All the results obtained in this line have had a direct transfer to our clinical care practice.
  • Pharmacokinetic personalized medicine: According to the Canadian National Research Council, Personalized Medicine supposes the adaptation of medical treatment to the individual characteristics of each patient. This implies the possibility of identifying patients who differ in their susceptibility to experience a certain disease, in the biology and/or prognosis of said disease, as well as in the response or adverse effects that they experience after the administration of a certain treatment. This identification is made through the analysis and integration of genomic data and molecular imaging techniques with clinical data and the patient’s environment.
  • Independent clinical research: Clinical trials are considered essential to advance scientific research. Thanks to them, new medicines and treatments may be available, but their implementation and execution is expensive for this reason, in more than 70% of cases they are usually promoted by the industry. In recent years, the unit has coordinated several of these trials; however, in recent years the need to promote independent clinical research has arisen, which attempts to solve problems identified by professionals of the National Health System that affect their patients. Leading innovation in the area of ​​drug development and the application of personalized medicine techniques inherently includes the clinical evaluation of these interventions. Currently, the unit has coordinated the conduct of clinical trials promoted by the industry, and leads two clinical trials independent in the field of infectious diseases.


Research team
Zarra Ferro, Irene


Almuíña Varela, Pablo
Bandín Vilar, Enrique José
Bernárdez Ferrán, Beatriz
Busto Iglesias, Manuel
Cañizo Outeiriño, Antonio
Castro Balado, Ana
Cuartero Martínez, Andrea
Durán Piñeiro, Goretti
Fernández Ferreiro, Anxo (coord.)
Fraga Codesido, Jessica
García Quintanilla, Laura
Gil Martínez, María
Giráldez Montero, José María

González Barcia, Miguel
González Berdullas, Patricia
González López, Jaime
Hermelo Vidal, Gonzalo
Mateos Martín, Jesús
Mondelo García, Cristina
Rodríguez Fernández, Carmen Antía
Rodríguez Martínez, Lorena
Tellería Barcia, Olga
Toja Camba, Francisco José
Varela Rey, Iria 

External Collaborators
Lamas Díaz, María Jesús


  • Varela Rey I, Bandín Vilar EJ, Cantón Blanco A, Martinon Torres N, Amoedo Fariña B, Gayoso González D, Barrientos Lema I, de Moura Ramos JJ, Zarra Ferro I, González Barcia M, Mondelo García C, Martínez Olmos MÁ, Fernández Ferreiro A. NEmecum: digital tool to help the prescription and dispensation of enteral nutrition and infant nutrition formulas. Development, diffusion and analysis of results and usage data. Nutr Hosp. 2023 Aug 30. doi: 10.20960/nh.04720. Online ahead of print. PMID: 37705457
  • Rodríguez-Martínez L, Castro-Balado A, Hermelo-Vidal G, Bandín-Vilar E, Varela-Rey I, Toja-Camba FJ, Rodríguez-Jato T, Novo-Veleiro I, Varela-García PM, Zarra-Ferro I, González-Barcia M, Mondelo-García C, Mateos J, Fernández-Ferreiro A. Ampicillin Stability in a Portable Elastomeric Infusion Pump: A Step Forward in Outpatient Parenteral Antimicrobial Therapy. Pharmaceutics. 2023 Aug 8;15(8):2099. doi: 10.3390/pharmaceutics15082099. PMID: 37631313
  • Busto-Iglesias M, Rodríguez-Martínez L, Rodríguez-Fernández CA, González-López J, González-Barcia M, de Domingo B, Rodríguez-Rodríguez L, Fernández-Ferreiro A, Mondelo-García C. Perspectives of Therapeutic Drug Monitoring of Biological Agents in Non-Infectious Uveitis Treatment: A Review. Pharmaceutics. 2023 Feb 25;15(3):766. doi: 10.3390/pharmaceutics15030766. PMID: 36986627
  • Castro-Balado A, Novo-Veleiro I, Vázquez-Agra N, Barbeito-Castiñeiras G, Estany-Gestal A, Trastoy-Pena R, González-Barcia M, Zarra-Ferro I, Del Río-Garma MC, Crespo-Diz C, Delgado-Sánchez O, Otero-Espinar FJ, Mondelo-García C, Pose-Reino A, Fernández-Ferreiro A. Efficacy and Safety of Inhaled Ethanol in Early-Stage SARS-CoV-2 Infection in Older Adults: A Phase II Randomized Clinical Trial. Pharmaceutics. 2023 Feb 16;15(2):667. doi: 10.3390/pharmaceutics15020667. PMID: 36839987
  • Varela-Rey I, de la Iglesia D, San Bruno-Ruz A, Mejuto-Fernández R, Monteserín-Ron L, López-Diaz J, García-Salom P, González-Cantalapiedra A, Manuel Brea J, Piña-Márquez R, Díaz-Tomé V, González-Barcia M, Zarra-Ferro I, Mondelo-García C, Dominguez-Muñoz E, Otero-Espinar F, Fernández-Ferreiro A. Design and biopharmaceutical preclinical characterisation of a new thermosensitive hydrogel for the removal of gastric polyps. Int J Pharm. 2023 Mar 25;635:122706. doi: 10.1016/j.ijpharm.2023.122706. PMID: 36803925
  • Castro-Balado A, Bandín-Vilar E, Cuartero-Martínez A, García-Quintanilla L, Hermelo-Vidal G, García-Otero X, Rodríguez-Martínez L, Mateos J, Hernández-Blanco M, Aguiar P, Zarra-Ferro I, González-Barcia M, Mondelo-García C, Otero-Espinar FJ, Fernández-Ferreiro A. Cysteamine Eye Drops in Hyaluronic Acid Packaged in Innovative Single-Dose Systems: Stability and Ocular Biopermanence. Pharmaceutics. 2022 Oct 15;14(10):2194. doi: 10.3390/pharmaceutics14102194. PMID: 36297629
  • Bandín-Vilar E, García-Quintanilla L, Castro-Balado A, Zarra-Ferro I, González-Barcia M, Campos-Toimil M, Mangas-Sanjuan V, Mondelo-García C, Fernández-Ferreiro A. A Review of Population Pharmacokinetic Analyses of Linezolid. Clin Pharmacokinet. 2022 Jun;61(6):789-817. doi: 10.1007/s40262-022-01125-2. Epub 2022 Jun 14. PMID: 35699914
  • García-Quintanilla L, Rodríguez-Martínez L, Bandín-Vilar E, Gil-Martínez M, González-Barcia M, Mondelo-García C, Fernández-Ferreiro A, Mateos J. Recent Advances in Proteomics-Based Approaches to Studying Age-Related Macular Degeneration: A Systematic Review. Int J Mol Sci. 2022 Nov 25;23(23):14759. doi: 10.3390/ijms232314759. PMID: 36499086